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The Process Analytical Technology initiative and multivariate process analysis, monitoring and control

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Abstract

Process analytical technology is an essential step forward in pharmaceutical industry. Real-time analyzers will provide timely data on quality properties. This information combined with process data (temperatures, flow rates, pressure readings) collected in real time can become a powerful tool for this industry, for process understanding, process and quality monitoring, abnormal situation detection and for improving product quality and process reliability. A very important tool for this achievement is the multivariate analysis.

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Authors and Affiliations

  1. Chemical Engineering Department, McMaster University, Hamilton, Ontario, L8S 4L7, Canada

    Theodora Kourti

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  1. Theodora Kourti
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Correspondence to Theodora Kourti.

Additional information

Dr. Theodora Kourti is Research Manager in the McMaster Advanced Control Consortium (MACC) and Adjunct Professor in the Chemical Engineering Department at McMaster University. She is the co-recipient of the 2003 University – Industry Synergy Award for Innovation, given by the Natural Science & Engineering Research Council of Canada. Dr. Kourti has been working on Multivariate Statistical Methods for Process and Product Improvement and Abnormal Situation Detection in Process Industries since 1992 and has been involved in more than 80 major industrial applications in North America and Europe. These are either off-line or real-time applications for batch and continuous processes, in diverse industries such as Chemicals, Pharmaceuticals, Semiconductor, Mining, Pulp and Paper, Petrochemicals, Photographic and Steel Industry. She has published extensively in this area and has provided training for numerous industrial practitioners.

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Kourti, T. The Process Analytical Technology initiative and multivariate process analysis, monitoring and control. Anal Bioanal Chem 384, 1043–1048 (2006). https://doi.org/10.1007/s00216-006-0303-y

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  • DOI: https://doi.org/10.1007/s00216-006-0303-y

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