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Flow injection analysis of gallic acid with inhibited electrochemiluminescence detection

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Abstract

A flow injection (FI)–electrochemiluminescent (ECL) method has been developed for the determination of gallic acid, based on an inhibition effect on the Ru(bpy)3 2+/tri-n-propylamine (TPrA) ECL system in pH 8.0 phosphate buffer solution. The method is simple and convenient with a determination limit of 9.0×10−9 mol/L and a dynamic concentration range of 2×10−8–2×10−5 mol/L. The relative standard deviation (RSD) was 1.0% for 1.0×10−6 mol/L gallic acid (n=11). It was successfully applied to the determination of gallic acid in Chinese proprietary medicine—Jianming Yanhou Pian. The inhibition mechanism proposed for the quenching effect of the gallic acid on the Ru(bpy)3 2+/TPrA ECL system was the interaction of electrogenerated Ru(bpy)3 2+* and o-benzoquinone derivative at the electrode surface. The ECL emission spectra and UV-visible absorption spectra were applied to confirm the mechanism.

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Acknowledgements

Financial support from NSFC (Grant No. 29875025) and MEC (Grant No. 2000035816) is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, University of Science and Technology of China, Hefei, 230026, Anhui, China

    Xiang-Qin Lin, Feng Li, Yong-Qiang Pang & Hua Cui

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  1. Xiang-Qin Lin
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  2. Feng Li
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  3. Yong-Qiang Pang
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  4. Hua Cui
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Correspondence to Xiang-Qin Lin.

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Lin, XQ., Li, F., Pang, YQ. et al. Flow injection analysis of gallic acid with inhibited electrochemiluminescence detection. Anal Bioanal Chem 378, 2028–2033 (2004). https://doi.org/10.1007/s00216-004-2519-z

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  • DOI: https://doi.org/10.1007/s00216-004-2519-z

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