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The reverse auto-compression system: a new type of column for preparative liquid chromatography

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Abstract

Axial compression of the stationary phase is an easy technique for packing preparative liquid chromatography columns. However, the compression piston often needs an important external device to move the external jack. A new type of column is described which uses an auto-compression system to move the piston and compress the packing material. The system is fitted with a new annular injector which is known to reduce the peak tailing. The results of the tests demonstrate the ease of use of this column, its efficiency and stability.

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Acknowledgements

The authors acknowledge Precision Instruments (Marseille, France) for the financial support and the commercial development of the reverse auto-compression system.

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Authors and Affiliations

  1. Laboratoire LI2C, Université Pierre et Marie Curie, 4 Place Jussieu, Boite 51, 75252 CEDEX 05, Paris, France

    François Dardoize, Gilles Clodic & Jean Chevalet

Authors
  1. François Dardoize
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  2. Gilles Clodic
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  3. Jean Chevalet
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Corresponding author

Correspondence to François Dardoize.

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Dardoize, F., Clodic, G. & Chevalet, J. The reverse auto-compression system: a new type of column for preparative liquid chromatography. Anal Bioanal Chem 375, 112–119 (2003). https://doi.org/10.1007/s00216-002-1656-5

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  • DOI: https://doi.org/10.1007/s00216-002-1656-5

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