Abstract
Summary
A recent survey of bone mineral density (BMD) in China recruited 7,042 healthy Han Chinese aged 20 years and older. The mean BMDs were different in gender, age, and region; the proportions of men and women older than 50 years with a high risk of osteoporosis were estimated as 10.4% and 31.2%, respectively
Introduction
A survey of BMD was completed during 2002–2006 in China. By three-stage sampling, a total of 7,042 healthy Han Chinese aged 20 years and older were recruited in ten cities: 2,694 subjects from Beijing, Tianjin, Haerbin, Lanzhou, and Yantai of northern China and 4,348 from Shanghai, Changsha, Chengdu, Haikou, and Foshan of southern China.
Methods
Two dual X-ray absorptiometry (DXA) systems (Hologic and Lunar) were used with parallel measurements of the European spine phantoms in each center. The mean BMDs in age groups older than 50 and the peak bone mineral density (pBMD) at femoral neck and that at greater trochanter were higher for men than women, and the pBMDs for northern China were higher than those for southern China, ranging from 1% to 4%.
Discussion and conclusion
This work has provided two useful references for the first time: one is the estimation of the proportion and number of individuals older than 50 years with a high risk of osteoporosis, 10.4% and 12.5 million men, 31.2% and 37.2 million women, which is important for health care planning and marketing projections, and another is the conversion equations for cross-calibration among different types of DXA instruments frequently used in China.
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Acknowledgment
We sincerely thank the Ministry of Health, People's Republic of China for the approval and guidance of this project. In addition to the authors of this paper, we appreciate the following colleagues who generously contributed to this project: SUN Tiansheng (Orthopedic Department of Beijing Army General Hospital), TAO Tianzun (The Second Affiliated Hospital of Harbin Medical University), CAO Haiwei (Foshan Chinese Tradition Medical Hospital), WANG Li (Tianjing Hospital), QIN Linlin (China–Japan Friendship Hospital), DENG Hongwen (Life Science Department of Hunan Normal University), ZHANG Shou and CHEN Wenyuan (Haikou Municipal Hospital), XIA Yayi (The Second Hospital of Lanzhou University), HU Zhenming (Beijing Friendship Hospital, Capital Medical University), ZHANG Shudong (Yantai City Yantai Shan Hospital), LI Jing (First Hospital of Peking University), SHI Huipeng (Shanghai 6th Peoples Hospital of Jiaotong University), and ZHU Xiaoying (Clinical and Research Center on Osteoporosis, East China Hospital, Fu Dan University).
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ZHU Hanmin and FANG Jiqian contributed equally to this work. A part of the preliminary results has been reported in international conferences: 2005 International Osteoporosis Conference, Hangzhou, China; 2006 International Osteoporosis Conference, Chengdu,China; 2007 International Osteoporosis Conference, Beijing, China; International Society For Clinical Densitometry(ISCD) 12th annual meeting, San Diego, USA.
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Zhu, H., Fang, J., Luo, X. et al. A survey of bone mineral density of healthy Han adults in China. Osteoporos Int 21, 765–772 (2010). https://doi.org/10.1007/s00198-009-1010-2
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DOI: https://doi.org/10.1007/s00198-009-1010-2