Skip to main content

Advertisement

Log in

The effect of pelvic floor muscle training for women with pelvic organ prolapse: a meta-analysis

  • Review Article
  • Published:
International Urogynecology Journal Aims and scope Submit manuscript

Abstract

Introduction and hypothesis

This study was aimed at evaluating the effect of pelvic floor muscle training (PFMT) as a conservative treatment for patients with pelvic organ prolapse (POP).

Methods

A comprehensive search to identify eligible randomized controlled trial (RCT) studies was conducted using electronic databases including PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Embase up to 10 June 2021. Results were presented as risk ratio (RR), the weighted mean difference (WMD), with 95% confidence interval (95% CI) using the random effects model. Outcome variables were pooled using Review Manager version 5.3.

Results

Thirteen studies were included. Our results demonstrated that women who received PFMT intervention had a greater improvement than controls in prolapse symptom score (POP-SS; mean difference [MD] −1.66, 95% CI −2.36 to −0.97, p < 0.00001] and POP stages (risk ration [RR] 1.51, 95% CI 1.14–2.01, p = 0.004). The number of participants who felt better after PFMT was higher (RR 1.98, 95% CI 1.21–3.24, p = 0.006). Subgroup analysis showed that the symptoms of prolapse and the degree of prolapse were improved significantly in the short term, but there was no significant difference in the long-term effect. In addition, there was no significant difference in the impact of PFMT on the elderly and the quality of life. More RCTs are needed to evaluate the effect of PFMT on the elderly and whether the quality of life can be improved.

Conclusions

We found that PFMT can improve subjective symptoms and objective POP severity. More research is needed on the long-term effect.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. ACOG technical bulletin. Pelvic organ prolapse. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet. 1996;52(2):197–205.

    Article  Google Scholar 

  2. Bump RC, Mattiasson A, Bø K, et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996;175(1):10–7. https://doi.org/10.1016/s0002-9378(96)70243-0.

    Article  CAS  PubMed  Google Scholar 

  3. Ghetti C, Gregory WT, Edwards SR, Otto LN, Clark AL. Pelvic organ descent and symptoms of pelvic floor disorders. Am J Obstet Gynecol. 2005;193(1):53–7. https://doi.org/10.1016/j.ajog.2004.12.004.

    Article  PubMed  Google Scholar 

  4. Pelvic Organ Prolapse. ACOG Practice Bulletin, Number 214. Obstet Gynecol. 2019;134(5):e126–42. https://doi.org/10.1097/aog.0000000000003519.

    Article  Google Scholar 

  5. Nygaard I, Barber MD, Burgio KL, et al. Prevalence of symptomatic pelvic floor disorders in US women. JAMA. 2008;300(11):1311–6. https://doi.org/10.1001/jama.300.11.1311.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Altman D, Forsman M, Falconer C, Lichtenstein P. Genetic influence on stress urinary incontinence and pelvic organ prolapse. Eur Urol. 2008;54(4):918–22. https://doi.org/10.1016/j.eururo.2007.12.004.

    Article  PubMed  Google Scholar 

  7. Mouritsen L, Larsen JP. Symptoms, bother and POPQ in women referred with pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2003;14(2):122–7. https://doi.org/10.1007/s00192-002-1024-1.

    Article  PubMed  Google Scholar 

  8. Wu JM, Vaughan CP, Goode PS, et al. Prevalence and trends of symptomatic pelvic floor disorders in U.S. women. Obstet Gynecol. 2014;123(1):141–8. https://doi.org/10.1097/aog.0000000000000057.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Wu JM, Matthews CA, Conover MM, Pate V, Jonsson Funk M. Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery. Obstet Gynecol. 2014;123(6):1201–6. https://doi.org/10.1097/aog.0000000000000286.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Yimphong T, Temtanakitpaisan T, Buppasiri P, Chongsomchai C, Kanchaiyaphum S. Discontinuation rate and adverse events after 1 year of vaginal pessary use in women with pelvic organ prolapse. Int Urogynecol J. 2018;29(8):1123–8. https://doi.org/10.1007/s00192-017-3445-x.

    Article  PubMed  Google Scholar 

  11. Dumoulin C, Cacciari LP, Hay-Smith EJC. Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women. Cochrane Database Syst Rev. 2018;10(10):CD005654. https://doi.org/10.1002/14651858.CD005654.pub4.

    Article  PubMed  Google Scholar 

  12. Stüpp L, Resende AP, Oliveira E, Castro RA, Girão MJ, Sartori MG. Pelvic floor muscle training for treatment of pelvic organ prolapse: an assessor-blinded randomized controlled trial. Int Urogynecol J. 2011;22(10):1233–9. https://doi.org/10.1007/s00192-011-1428-x.

    Article  PubMed  Google Scholar 

  13. Alves FK, Riccetto C, Adami DB, et al. A pelvic floor muscle training program in postmenopausal women: A randomized controlled trial. Maturitas. 2015;81(2):300–5. https://doi.org/10.1016/j.maturitas.2015.03.006.

    Article  PubMed  Google Scholar 

  14. Ouchi M, Kato K, Gotoh M, Suzuki S. Physical activity and pelvic floor muscle training in patients with pelvic organ prolapse: a pilot study. Int Urogynecol J. 2017;28(12):1807–15. https://doi.org/10.1007/s00192-017-3356-x.

    Article  PubMed  Google Scholar 

  15. Liu YJ, Ting SW, Hsiao SM, Huang CM, Wu WY. Efficacy of bio-assisted pelvic floor muscle training in women with pelvic floor dysfunction. Eur J Obstet Gynecol Reprod Biol. 2020;251:206–11. https://doi.org/10.1016/j.ejogrb.2020.04.050.

    Article  PubMed  Google Scholar 

  16. Bø K. Pelvic floor muscle training is effective in treatment of female stress urinary incontinence, but how does it work? Int Urogynecol J Pelvic Floor Dysfunct. 2004;15(2):76–84. https://doi.org/10.1007/s00192-004-1125-0.

    Article  PubMed  Google Scholar 

  17. Hagen S, Stark D. Conservative prevention and management of pelvic organ prolapse in women. Cochrane Database Syst Rev. 2011;12:CD003882. https://doi.org/10.1002/14651858.CD003882.pub4.

    Article  Google Scholar 

  18. Li C, Gong Y, Wang B. The efficacy of pelvic floor muscle training for pelvic organ prolapse: a systematic review and meta-analysis. Int Urogynecol J. 2016;27(7):981–92. https://doi.org/10.1007/s00192-015-2846-y.

    Article  PubMed  Google Scholar 

  19. Ge J, Wei XJ, Zhang HZ, Fang GY. Pelvic floor muscle training in the treatment of pelvic organ prolapse: a meta-analysis of randomized controlled trials. Actas Urol Esp (Engl Ed). 2021;45(1):73–82. https://doi.org/10.1016/j.acuro.2020.01.012.

    Article  CAS  Google Scholar 

  20. Hagen S, Glazener C, Sinclair L, Stark D, Bugge C. Psychometric properties of the pelvic organ prolapse symptom score. BJOG. 2009;116(1):25–31. https://doi.org/10.1111/j.1471-0528.2008.01903.x.

    Article  CAS  PubMed  Google Scholar 

  21. Barber MD, Walters MD, Bump RC. Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7). Am J Obstet Gynecol. 2005;193(1):103–13. https://doi.org/10.1016/j.ajog.2004.12.025.

    Article  CAS  PubMed  Google Scholar 

  22. Higgins JP, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. https://doi.org/10.1136/bmj.d5928.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Hagen S, Stark D, Glazener C, Sinclair L, Ramsay I. A randomized controlled trial of pelvic floor muscle training for stages I and II pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20(1):45–51. https://doi.org/10.1007/s00192-008-0726-4.

    Article  PubMed  Google Scholar 

  24. Braekken IH, Majida M, Engh ME, Bø K. Can pelvic floor muscle training reverse pelvic organ prolapse and reduce prolapse symptoms? An assessor-blinded, randomized, controlled trial. Am J Obstet Gynecol. 2010;203(2):170.e1–7. https://doi.org/10.1016/j.ajog.2010.02.037.

    Article  Google Scholar 

  25. Kashyap R, Jain V, Singh A. Comparative effect of 2 packages of pelvic floor muscle training on the clinical course of stage I–III pelvic organ prolapse. Int J Gynaecol Obstet. 2013;121(1):69–73. https://doi.org/10.1016/j.ijgo.2012.11.012.

    Article  PubMed  Google Scholar 

  26. Hagen S, Stark D, Glazener C, et al. Individualised pelvic floor muscle training in women with pelvic organ prolapse (POPPY): a multicentre randomized controlled trial. Lancet. 2014;383(9919):796–806. https://doi.org/10.1016/S0140-6736%2813%2961977-7.

    Article  PubMed  Google Scholar 

  27. Due U, Brostrøm S, Lose G. Lifestyle advice with or without pelvic floor muscle training for pelvic organ prolapse: a randomized controlled trial. Int Urogynecol J. 2016;27(4):555–63. https://doi.org/10.1007/s00192-015-2852-0.

    Article  PubMed  Google Scholar 

  28. Panman CM, Wiegersma M, Kollen BJ, et al. Effectiveness and cost-effectiveness of pessary treatment compared with pelvic floor muscle training in older women with pelvic organ prolapse: 2-year follow-up of a randomized controlled trial in primary care. Menopause. 2016;23(12):1307–18. https://doi.org/10.1097/gme.0000000000000706.

    Article  PubMed  Google Scholar 

  29. Panman C, Wiegersma M, Kollen BJ, et al. Two-year effects and cost-effectiveness of pelvic floor muscle training in mild pelvic organ prolapse: a randomised controlled trial in primary care. BJOG. 2017;124(3):511–20. https://doi.org/10.1111/1471-0528.13992.

    Article  PubMed  Google Scholar 

  30. Due U, Brostrøm S, Lose G. The 12-month effects of structured lifestyle advice and pelvic floor muscle training for pelvic organ prolapse. Acta Obstet Gynecol Scand. 2016;95(7):811–9. https://doi.org/10.1111/aogs.12884.

    Article  PubMed  Google Scholar 

  31. Hagen S, Glazener C, McClurg D, et al. Pelvic floor muscle training for secondary prevention of pelvic organ prolapse (PREVPROL): a multicentre randomised controlled trial. Lancet. 2017;389(10067):393–402. https://doi.org/10.1016/s0140-6736(16)32109-2.

    Article  PubMed  Google Scholar 

  32. Resende APM, Bernardes BT, Stüpp L, et al. Pelvic floor muscle training is better than hypopressive exercises in pelvic organ prolapse treatment: An assessor-blinded randomized controlled trial. Neurourol Urodyn. 2019;38(1):171–9. https://doi.org/10.1002/nau.23819.

    Article  PubMed  Google Scholar 

  33. Wiegersma M, Panman CM, Kollen BJ, Berger MY, Lisman-Van Leeuwen Y, Dekker JH. Effect of pelvic floor muscle training compared with watchful waiting in older women with symptomatic mild pelvic organ prolapse: randomised controlled trial in primary care. BMJ. 2014;349:g7378. https://doi.org/10.1136/bmj.g7378.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Burgio KL, Goode PS, Richter HE, Locher JL, Roth DL. Global ratings of patient satisfaction and perceptions of improvement with treatment for urinary incontinence: validation of three global patient ratings. Neurourol Urodyn. 2006;25(5):411–7. https://doi.org/10.1002/nau.20243.

    Article  PubMed  Google Scholar 

  35. Basnet R. Impact of pelvic floor muscle training in pelvic organ prolapse. Int Urogynecol J. 2021;32(6):1351–60. https://doi.org/10.1007/s00192-020-04613-w.

    Article  PubMed  Google Scholar 

  36. Fine P, Burgio K, Borello-France D, et al. Teaching and practicing of pelvic floor muscle exercises in primiparous women during pregnancy and the postpartum period. Am J Obstet Gynecol. 2007;197(1):107.e101–5. https://doi.org/10.1016/j.ajog.2007.02.052.

    Article  Google Scholar 

  37. NICE Guidance—Urinary incontinence and pelvic organ prolapse in women: management: © NICE. Urinary incontinence and pelvic organ prolapse in women: management. BJU Int. 2019;123(5):777–803. https://doi.org/10.1111/bju.14763.

    Article  Google Scholar 

  38. Wiegersma M, Panman C, Hesselink LC, Malmberg AGA, Berger MY, Kollen BJ, et al. Predictors of success for pelvic floor muscle training in pelvic organ prolapse. Phys Ther. 2019;99(1):109–17. https://doi.org/10.1093/ptj/pzy114.

    Article  PubMed  Google Scholar 

  39. Jackson SR, Avery NC, Tarlton JF, Eckford SD, Abrams P, Bailey AJ. Changes in metabolism of collagen in genitourinary prolapse. Lancet. 1996;347(9016):1658–61. https://doi.org/10.1016/s0140-6736(96)91489-0.

    Article  CAS  PubMed  Google Scholar 

  40. Tosun Ö, Mutlu EK, Tosun G, et al. Do stages of menopause affect the outcomes of pelvic floor muscle training? Menopause. 2015;22(2):175–84. https://doi.org/10.1097/gme.0000000000000278.

    Article  PubMed  Google Scholar 

  41. Roovers JP. Female urology: the benefits of pelvic floor muscle training for prolapse. Nat Rev Urol. 2014;11(4):192–3. https://doi.org/10.1038/nrurol.2014.35.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We thank Mr Z.B. Wang in Beijing University of Chinese Medicine for his kind advice on the project and writing assistance.

Author information

Authors and Affiliations

Authors

Contributions

Ting Wang: project development, data collection, manuscript writing; Zhengfang Wen: manuscript revision; Meng Li: data collection.

Corresponding author

Correspondence to Zhengfang Wen.

Ethics declarations

Conflicts of interest

None.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

ESM 1

(DOC 34 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, T., Wen, Z. & Li, M. The effect of pelvic floor muscle training for women with pelvic organ prolapse: a meta-analysis. Int Urogynecol J 33, 1789–1801 (2022). https://doi.org/10.1007/s00192-022-05139-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00192-022-05139-z

Keywords

Navigation