Skip to main content
Log in

One-year clinical and MR imaging outcome after partial meniscal replacement in stabilized knees using a collagen meniscus implant

  • Knee
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Purpose

The purpose of the study was to evaluate the clinical and radiological outcomes after medial/lateral collagen meniscus substitution (CMI) at 12 months postoperatively.

Methods

Sixty-seven patients (m:f = 47:20, mean age 36 ± 10 years) underwent arthroscopic CMI after previous subtotal medial (n = 55) or lateral meniscectomy (n = 12) due to persistent joint line pain (n = 25) or to prophylactic reasons (n = 42). Clinical follow-up consisted of IKDC score, Tegner score, Lysholm score, and visual analog scale for pain and satisfaction (preinjury, preoperatively, and 12 months postoperatively; follow-up rate 90 %). MRI scans were analyzed according to the Genovese criteria.

Results

Nineteen patients (29 %) showed a normal (A), 35 nearly normal (B), 5 abnormal (C), and 1 patient severely abnormal total IKDC score (D). The median Tegner preinjury score was 7 (range 2–10) and at follow-up 6 (range 2–10). The mean Lysholm score before surgery was 68 ± 20 and 93 ± 9 at follow-up. Preoperatively, the mean VAS pain was 4.4 ± 3.1 and 2.0 ± 1.0 at follow-up. Clinical failure of the CMI occurred in 3 patients (n = 1 infection, n = 1 failure of the implant, n = 1 chronic synovitis). On MRI, the CMI was completely resorbed in 3 patients (5 %), partially resorbed in 55 (92 %), and entirely preserved in 3 (5 %) patients. In 5 patients (8 %) the CMI was isointense, in 54 (90 %) slightly and 1 (2 %) highly hyperintense. 43 (72 %) patients showed an extrusion of the CMI implant of more than 3 mm.

Conclusions

Significant pain relief and functional improvement throughout all scores at 1 year was noted. The CMI undergoes significant remodeling, degradation, resorption, and extrusion in most of the patients. No difference in outcomes between the medial and lateral CMI was observed.

Level of evidence

Prospective therapeutic study, Level IV.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Adams JG, McAlindon T, Dimasi M, Carey J, Eustace S (1999) Contribution of meniscal extrusion and cartilage loss to joint space narrowing in osteoarthritis. Clin Radiol 54:502–506

    Article  PubMed  CAS  Google Scholar 

  2. Arnold MP, Hirschmann MT, Verdonk PC (2012) See the whole picture: knee preserving therapy needs more than surface repair. Knee Surg Sports Traumatol Arthrosc 20:195–196

    Article  PubMed  Google Scholar 

  3. Bulgheroni P, Murena L, Ratti C, Bulgheroni E, Ronga M, Cherubino P (2010) Follow-up of collagen meniscus implant patients: clinical, radiological, and magnetic resonance imaging results at 5 years. Knee 17:224–229

    Article  PubMed  Google Scholar 

  4. Genovese E, Angeretti MG, Ronga M, Leonardi A, Novario R, Callegari L, Fugazzola C (2007) Follow-up of collagen meniscus implants by MRI. Radiol Med 112:1036–1048

    Article  PubMed  CAS  Google Scholar 

  5. Hannink G, van Tienen TG, Schouten AJ, Buma P (2011) Changes in articular cartilage after meniscectomy and meniscus replacement using a biodegradable porous polymer implant. Knee Surg Sports Traumatol Arthrosc 20:1881–1882

    Article  Google Scholar 

  6. Harston A, Nyland J, Brand E, McGinnis M, Caborn DN (2012) Collagen meniscus implantation: a systematic review including rehabilitation and return to sports activity. Knee Surg Sports Traumatol Arthrosc 20:135–146

    Article  PubMed  Google Scholar 

  7. Kim JM, Lee BS, Kim KH, Kim KA, Bin SI (2012) Results of meniscus allograft transplantation using bone fixation: 110 cases with objective evaluation. Am J Sports Med 40:1027–1034

    Article  PubMed  Google Scholar 

  8. Lee DH, Lee BS, Chung JW, Kim JM, Yang KS, Cha EJ, Bin SI (2011) Changes in magnetic resonance imaging signal intensity of transplanted meniscus allografts are not associated with clinical outcomes. Arthroscopy 27:1211–1218

    Article  PubMed  Google Scholar 

  9. Linke RD, Ulmer M, Imhoff AB (2006) Replacement of the meniscus with a collagen implant (CMI). Oper Orthop Traumatol 18:453–462

    Article  PubMed  Google Scholar 

  10. Lysholm J, Gillquist J (1982) Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med 10:150–154

    Article  PubMed  CAS  Google Scholar 

  11. Marcacci M, Zaffagnini S, Marcheggiani Muccioli GM, Grassi A, Bonanzinga T, Nitri M, Bondi A, Molinari M, Rimondi E (2012) Meniscal allograft transplantation without bone plugs: a 3-year minimum follow-up study. Am J Sports Med 40:395–403

    Article  PubMed  Google Scholar 

  12. Monllau JC, Gelber PE, Abat F, Pelfort X, Abad R, Hinarejos P, Tey M (2011) Outcome after partial medial meniscus substitution with the collagen meniscal implant at a minimum of 10 years’ follow-up. Arthroscopy 27:933–943

    Article  PubMed  Google Scholar 

  13. Puig L, Monllau JC, Corrales M, Pelfort X, Melendo E, Caceres E (2006) Factors affecting meniscal extrusion: correlation with MRI, clinical, and arthroscopic findings. Knee Surg Sports Traumatol Arthrosc 14:394–398

    Article  PubMed  Google Scholar 

  14. Rodkey WG, DeHaven KE, Montgomery WH III, Baker CL Jr, Beck CL Jr, Hormel SE, Steadman JR, Cole BJ, Briggs KK (2008) Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial. J Bone Joint Surg Am 90:1413–1426

    Article  PubMed  Google Scholar 

  15. Rodkey WG, Steadman JR, Li ST (1999) A clinical study of collagen meniscus implants to restore the injured meniscus. Clin Orthop Relat Res 367:S281–S292

    Article  PubMed  Google Scholar 

  16. Ronga M, Grassi FA, Bulgheroni P (2004) Arthroscopic autologous chondrocyte implantation for the treatment of a chondral defect in the tibial plateau of the knee. Arthroscopy 20:79–84

    Article  PubMed  Google Scholar 

  17. Tegner Y, Lysholm J (1985) Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res 198:43–49

    PubMed  Google Scholar 

  18. Verdonk P, Beaufils P, Bellemans J, Djian P, Heinrichs EL, Huysse W, Laprell H, Siebold R, Verdonk R (2012) Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes. Am J Sports Med 40:844–853

    Article  PubMed  Google Scholar 

  19. Zaffagnini S, Giordano G, Vascellari A, Bruni D, Neri MP, Iacono F, Kon E, Presti ML, Marcacci M (2007) Arthroscopic collagen meniscus implant results at 6 to 8 years follow up. Knee Surg Sports Traumatol Arthrosc 15:175–183

    Article  PubMed  Google Scholar 

  20. Zaffagnini S, Marcheggiani Muccioli GM, Grassi A, Bonanzinga T, Filardo G, Canales Passalacqua A, Marcacci M (2011) Arthroscopic lateral collagen meniscus implant in a professional soccer player. Knee Surg Sports Traumatol Arthrosc 19:1740–1743

    Article  PubMed  Google Scholar 

  21. Zaffagnini S, Marcheggiani Muccioli GM, Lopomo N, Bruni D, Giordano G, Ravazzolo G, Molinari M, Marcacci M (2011) Prospective long-term outcomes of the medial collagen meniscus implant versus partial medial meniscectomy: a minimum 10-year follow-up study. Am J Sports Med 39:977–985

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This study was supported by a financial grant from Ivy Sports Medicine, Baar, Switzerland for statistical analysis.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. T. Hirschmann.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hirschmann, M.T., Keller, L., Hirschmann, A. et al. One-year clinical and MR imaging outcome after partial meniscal replacement in stabilized knees using a collagen meniscus implant. Knee Surg Sports Traumatol Arthrosc 21, 740–747 (2013). https://doi.org/10.1007/s00167-012-2259-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00167-012-2259-0

Keywords

Navigation