Abstract
Exhaled nitric oxide is considered as a marker of airway inflammation. We report here our preliminary experience with single-breath exhaled nitric oxide measured in lung transplant patients with and without bronchiolitis obliterans syndrome and in cardiac transplant patients. Peak and end-expiratory nitric oxide concentrations did not differ between groups, but single-breath exhaled nitric oxide recordings were strikingly different in patients suffering from bronchiolitis obliterans syndrome, with a slower decrease from peak to end-expiratory nitric oxide concentration. Further studies are required in order to determine whether theses abnormalities reflect the inflammatory process of bronchiolitis obliterans syndrome.
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Received: 10 July 1998 Received after revision: 11 March 1999 Accepted: 4 May 1999
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Zegdi, R., Guillmain, R., Amrein, C. et al. Single breath exhaled nitric oxide in lung transplant patients: a preliminary clinical study. Transpl Int 12, 346–350 (1999). https://doi.org/10.1007/s001470050238
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DOI: https://doi.org/10.1007/s001470050238