Abstract
A 17-year-old patient with Shone's disease had to be readmitted to the hospital 3 months after implantation of an artificial aortic valve because of extreme mitral insufficiency with consecutive pulmonary edema and hepatic dysfunction. He had been orally anticoagulated and presented with a high international normalized ratio of 6.7. Emergency replacement of the mitral valve was possible only after administration of prothrombin-complex concentrate, as vitamin K1 and fresh frozen plasma did not correct the hemostatic defect sufficiently.
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Received: 14 October 1998/Accepted: 13 April 1999
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Rauch, R., Hofbeck, M., Ries, M. et al. Emergency correction of coagulation for mitral valve replacement in an orally anticoagulated 17-year-old patient with pronounced hepatic dysfunction. Intensive Care Med 25, 1131–1133 (1999). https://doi.org/10.1007/s001340051023
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DOI: https://doi.org/10.1007/s001340051023