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Intractable bleeding tendency due to acquired von Willebrand syndrome after Jarvik 2000 implant

  • Case Report
  • Artificial Heart (Clinical)
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Abstract

A 61-year-old man was implanted with a Jarvik 2000, a continuous axial flow type left ventricular assist device (LVAD), for end-stage heart failure due to dilated cardiomyopathy. One month later, his postoperative course was complicated with intractable oozing-type gastrointestinal bleeding from multiple small shallow ulcers and erosions in the colon. In addition, repeated bleeding episodes were encountered at around thoracentesis site for pleural effusion. Hematological examination showed that platelet counts and coagulation factors were kept within normal ranges. We, thereafter, revealed remarkable loss of the large multimers of von Willebrand factors (VWFs), which might be closely associated with his intractable bleeding tendency.

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Authors and Affiliations

  1. Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryocho, Aoba-ku, Sendai, 980-8574, Japan

    Ko Sakatsume, Masatoshi Akiyama, Shunsuke Kawamoto & Yoshikatsu Saiki

  2. Department of Molecular and Cellular Biology, Institute of Development, Aging, and Cancer, Tohoku University, 4-1 Seiryocho, Aoba-ku, Sendai, 980-8575, Japan

    Kenki Saito & Hisanori Horiuchi

Authors
  1. Ko Sakatsume
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  2. Masatoshi Akiyama
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  3. Kenki Saito
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  4. Shunsuke Kawamoto
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  5. Hisanori Horiuchi
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  6. Yoshikatsu Saiki
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Correspondence to Ko Sakatsume or Yoshikatsu Saiki.

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Sakatsume, K., Akiyama, M., Saito, K. et al. Intractable bleeding tendency due to acquired von Willebrand syndrome after Jarvik 2000 implant. J Artif Organs 19, 289–292 (2016). https://doi.org/10.1007/s10047-016-0896-7

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  • DOI: https://doi.org/10.1007/s10047-016-0896-7

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