Zusammenfassung
Die vorliegende Arbeit liefert eine Übersicht aktueller evidenzbasierter Daten und neuer, klinisch relevanter Entwicklungen auf dem Gebiet der Hüftendoprothetik. Eine Vielzahl aktueller klinischer Studien beschäftigte sich mit der Tribologie, und hier stehen insbesondere die Metall-Metall-Gleitpaarungen im Blickpunkt. Große Studien aus Prothesenregistern definierten Risikofaktoren für ein frühzeitiges Versagen beim Oberflächenersatz und das Auftreten von Pseudotumoren. Auch neue keramische Gleitpartner wurden in randomisierten Studien untersucht. Neben weiteren interessanten klinischen Studien liegen nun auch große Metaanalysen zur Infektdiagnostik, Antibiotikaprophylaxe, Regionalanästhesie, Thromboembolieprophylaxe, Prothesenfixation, Navigation sowie Komplikationsvermeidung vor, die in der vorliegenden Arbeit zusammengefasst wurden.
Abstract
The present manuscript provides an overview of current evidence-based data and new clinically relevant developments in the field of hip arthroplasty. A multitude of current clinical trials have focussed on tribology with special interest on metal-on-metal implants. Large trials from implant registries have defined specific risk factors for early implant failure and pseudotumors in surface replacement. Furthermore, new ceramic liners and femoral head implants have been investigated in randomized trials. Apart from other very interesting studies, the results of large meta-analyses are now available for laboratory values in periprosthetic infection, antibiotic prophylaxis, regional anesthesia, prevention of thromboembolism, implant fixation, navigation and clinical pathways to prevent complications.
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Gollwitzer, H., Gerdesmeyer, L., Gradinger, R. et al. Evidenzbasiertes Update aus der Hüftendoprothetik. Orthopäde 40, 535–542 (2011). https://doi.org/10.1007/s00132-011-1763-0
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DOI: https://doi.org/10.1007/s00132-011-1763-0
Schlüsselwörter
- Hüft-Totalendoprothese (Hüft-TEP)
- Evidenzbasierte Medizin (EBM)
- „Randomized controlled trial“ (RCT)
- Metaanalyse
- Systematisches Review