Skip to main content
Log in

Geschlechtsdetermination und Entwicklung der Genitalorgane

  • Published:
Der Urologe B

Zusammenfassung

Die Erkenntnisse der Grundlagenforschung zur Morphogenese der Genitalorgane sind für das Verständnis der klinischen Befunde bei Genitalmißbildungen und Intersexualitat von Wichtigkeit. Es wird insbesondere auf die morphologische Entwicklung der Gonaden, der Genitalgänge sowie der inneren und äußeren Genitalorgane eingegangen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Baker TG (1963) A quantitative and cytological study ofgerm cells in human ovaries. Proc R Soc Lond B 158: 417–133

    Article  CAS  PubMed  Google Scholar 

  2. Chwalla R (1927) Über die Entwicklung der Harnblaseund der primären Harnröhre des Menschen mit besonderer Berücksichtigungder Art und Weise, in der sich die Üreteren von den Ürnieren-gängen trennen,nebst Bemerkungen über die Entwicklung der Müllerschen Gange unddes Mastdarms. Z Anat Entwickl Gesch 83: 615–733

    Article  Google Scholar 

  3. Drews U (1976) Die Entwicklung der Sexualorgane:von der genetischen Information zur morphologischen Differenzierung. Gynäkologe 9: 3–15

    CAS  PubMed  Google Scholar 

  4. Drews U (1993) Taschenatlas der Embryologie. Thieme, Stuttgart New York

    Google Scholar 

  5. Godin I, Wylie CC (1991) TGF beta 1 inhibits proliferation and has a chemotropic effect on mouse primordial germ cells in culture. Development 113: 1451–1457

    CAS  PubMed  Google Scholar 

  6. Josso N (1992) Anti-mullerian hormone and Sertoli cell function. Horm Res 38 [Suppl 2]: 72–76

    Article  PubMed  Google Scholar 

  7. Koff A (1933) Development of the vagina in the human fetus. Contr Embryol Carnegie Inst 24: 59–60

    CAS  PubMed  Google Scholar 

  8. Koopman PJ, Gubbay N, Goodfellow VP, Lovell-Badge R (1991) Male development of chromosomally female mice transgenic for Sry. Nature 351: 117–121

    Article  CAS  PubMed  Google Scholar 

  9. Mauch RB, Thiedemann KU, Drews U; (1985) The vagina is formed by down-growth of Wolffian and Müllerian ducts: graphical reconstructions from normal and Tfm mouse embryos. Anat Embryol 172: 75–87

    Article  CAS  PubMed  Google Scholar 

  10. McLaren A, Simpson E, Epplen JT, Studer R, Koopman P, Evans EP, Burgoyne PS (1988) Location of the genes controlling H-Y antigen expression and testis determination on the mouse Y chromosome. Proc Natl Acad Sci USA 85: 6442–6445

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  11. McLaren A, Simpson E, Tomonari K, Chandler P, Hoog H (1984) Male sexual differentiation in mice lacking H-Y antigen. Nature 312: 552–553

    Article  CAS  PubMed  Google Scholar 

  12. O’Rahilly R (1983) The timing and sequence of events in the development of the human reproductive system during the embryonic period proper. Anat Embryol 166: 247–261

    Article  PubMed  Google Scholar 

  13. O’Rahilly R, Müller R (1987) Developmental stages in human embryos. Carnegie Inst Washington, Publication No 637

  14. Terruhn V (1980) A study of impression moulds of the genital tract of female fetuses. Arch Gynecol 229: 207–217

    Article  CAS  PubMed  Google Scholar 

  15. Wachtel SS, Ohno S, Koo GC, Boyse EA (1975) Possible role of H-Y antigen in the primary determination of sex. Nature 257: 235–236

    Article  CAS  PubMed  Google Scholar 

  16. Whitefield LS, Lovell-Badge RP, Goodfellow N (1993) Rapid sequence evolution of the mammalian sex-determing gene SRY. Nature 364: 713–715

    Article  Google Scholar 

  17. Witschi E (1970) Development and differentiation of the uterus. In: Mack HC (ed) Prenatal Life. Wayne State University Press, Detroit, pp 11–34

    Google Scholar 

  18. Witschi E (1948) Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds. Contr Embryol Carnegie Inst 32: 67–80

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Drews, U. Geschlechtsdetermination und Entwicklung der Genitalorgane. Der Urologe B 37, 2–8 (1997). https://doi.org/10.1007/s001310050054

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s001310050054

Navigation