Study population
We used baseline data from the Healthy Life in an Urban Setting (HELIUS) study, a multi-ethnic cohort study in Amsterdam, the Netherlands. The full study protocol is described elsewhere [2]. Briefly, participants aged 18–70 years were randomly sampled stratified by ethnic origin through the municipality register of Amsterdam. This register includes data on the country of birth of residents and their parents, which were used to determine ethnicity (see below). We were able to contact about 65 % of those invited (Surinamese 73 %, Ghanaians 69 %, Turks 60 %, Moroccans 66 %), either by response card or after home visit by an ethnically-matched interviewer. Of those contacted, about 42 % agreed to participate (Surinamese 43 %, Ghanaians 50 %, Turks 34 %, Moroccans 32 %). After positive response, participants received a digital or paper version of the questionnaire (depending on the preference). Participants who were unable to complete the questionnaire themselves were offered assistance from a trained ethnically-matched interviewer. Data collection was still on going at the time of data analysis for this study. Written informed consent was obtained from all participants prior to the study inclusion.
Baseline data were collected from January 2011 until June 2014. From the total sample (n = 14,628), we excluded ethnic Dutch (n = 2192). From the remaining ethnic minority groups, we excluded Surinamese with Indonesian origin (n = 148) and with unknown origin (n = 151), and those with unknown ethnic background (n = 29), as these groups were relatively small. Subsequently, participants were excluded with missing data on PED, depression and/or education (n = 328). This finally resulted in 11,780 participants: 2501 South-Asian Surinamese, 2292 African Surinamese, 1877 Ghanaians, 2626 Turks, and 2484 Moroccans.
Variables
Ethnicity
Participant’s ethnicity was defined according to the country of birth of the participants as well as that his parents [36]. Specifically, a participant was considered of non-Dutch ethnicity if either of the following criteria was fulfilled: (1) born outside the Netherlands and at least one parent born outside the Netherlands (i.e., first generation); or (2) born in the Netherlands, but both parents born outside the Netherlands (i.e., second generation). In addition, self-reported ethnicity was used to determine Surinamese subgroups (either African or South-Asian origin).
Perceived ethnic discrimination
PED was conceptualized as the day-to-day experiences of unfair treatment (both overt and subtle) because of ethnic background [9]. To measure PED we used the Everyday Discrimination Scale (EDS), a widely used scale in US studies [37, 38]. The EDS is developed based on a qualitative study among African American women, but also in African Surinamese women in the Netherlands [16], suggesting that the EDS can be used among ethnic minority groups in European settings as well. The EDS captures the frequency of experiences of discrimination in everyday life, using nine items (e.g., “being treated with less respect than others”). We adapted the EDS such that the participants were specifically asked about discriminatory experiences because of their ethnic background. The response scale for each item varied from 1 (never) to 5 (very often), consistent with the study by Forman et al. [37]. The mean discrimination score of the nine items was calculated (1 = lowest, 5 = highest) and used in the analyses. The Cronbach’s alpha was 0.91 for South-Asian Surinamese, 0.90 for African Surinamese, 0.91 for Ghanaians, 0.90 for Turks, and 0.92 for Moroccans.
Depressive symptoms
Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9) [39]. The PHQ-9 assesses the presence of depressive symptoms over the preceding 2 weeks. Baas et al. demonstrated the validity of PHQ-9 among Surinamese in the Netherlands [40]. The PHQ-9 consists of nine items, with a response scale varying from 0 (never) to 3 (nearly every day). Hence the total sum score for depression symptoms varied between 0 (lowest) and 27 (highest). The Cronbach’s alpha was 0.92 for South-Asian Surinamese, 0.86 for African Surinamese, 0.87 for Ghanaians, 0.90 for Turks and 0.88 for Moroccans.
Educational level
Educational level was defined as the highest level of education completed with a diploma or certificate of proficiency, either in the Netherlands or in the country of origin. Based on the highest level of education completed, participants were divided into four categories: no education or elementary education; lower vocational and general secondary education; intermediate vocational and higher secondary education; and higher vocational education and university.
Ethnic identity
Ethnic identity was conceptualized as the sense of belonging to one’s own ethnic group that shares cultural values and beliefs [41, 42]. It reflects a sense of membership and the positive feelings toward one’s ethnic heritage and/or identity [21, 42]. It was measured using the 10 items of Psychological Acculturation Scale (PAS; e.g., “I have a lot in common with Surinamese/Ghanaian/Turkish/Moroccan people”, “I feel proud to be part of Surinamese/Ghanaian/Turkish/Moroccan culture”) [43]. We did not use the single self-identification item (e.g., “I feel Surinamese”), since it may fail to fully capture the multifaceted nature of ethnic identity, as conceptualized above [42]. A multidimensional scale as the PAS might work better as a measure for ethnic identity. For example, individuals might not necessarily identify themselves as Surinamese or Ghanaian, but psychologically they could be strongly connected to and find comfort within their own group. Furthermore, ethnic minority members may provide social desirable answers to the self-identification item. We may reduce this potential bias using a multi-item scale to assess ethnic identity. The response scale of PAS ranged from 1 (totally disagree) to 5 (totally agree), leading to a sum score varying between 10 (weakest ethnic identity) and 50 (strongest ethnic identity). For assessing effect modification, we decided to dichotomize ethnic identity after considering the sum score distribution within each ethnic minority group: <40 (weak ethnic identity) and ≥40 (strong ethnic identity). The Cronbach’s alpha was 0.93 for South-Asian Surinamese, 0.92 for African Surinamese, 0.94 for Ghanaians, 0.93 for Turks, and 0.92 for Moroccans.
Religion
Religion was conceptualized as currently practicing religion. It was measured using a single item, “Do you practice a specific religion right now?”, with yes/no response.
Ethnic social network
Ethnic social network was conceptualized as the presence of same-ethnic people within one’s social network [21]. We assessed ethnic social network using two proxy items on a 5-point Likert scale: (1) “I have Surinamese/Ghanaian/Turkish/Moroccans friends” (1 = none, 5 = very many), and 2) “I spend my free time with Surinamese/Ghanaian/Turkish/Moroccan people” (1 = never, 5 = always). We initially developed a composite variable, but since the Cronbach’s alpha was low in the ethnic minority groups (varying between 0.52 and 0.71), we decided to analyse these two variables separately. One variable concerned the number of same-ethnic friends and the other was related to leisure time spent with same-ethnic people. To test effect modification, we dichotomized both variables. Based on the score distributions, both items were dichotomized at the score of 4, with score of 4 or higher indicating high number of same-ethnic friends and often (or always) spending leisure time with same-ethnic people.
Statistical analysis
To handle missing data for PED, depression and ethnic identity, we employed the following strategy: if one of the items was missing, the mean score of the other eight items was used to replace the missing item. If more than one item was missing, the variable was considered missing. Data for ethnic identity, religion, and two ethnic social network measures were missing in less than 1 % of all participants, with little between-group variation (see also Table 1). These participants were excluded from the analyses that included these variables.
Table 1 Characteristics of the study population
Linear regressions were used to examine the association between PED and depressive symptoms. The normal probability plot (P–P plot) of residuals of depressive symptoms showed that this variable was about normally distributed. The regressions were estimated for the total sample and for each ethnic minority group separately. We performed the analyses with the total sample to increase the statistical power and to possibly identify any interaction effects which may be too small to be demonstrated in the group-specific analysis. The models were adjusted for ethnicity (only in the total sample), sex, age, migration generation, and education. In a previous study using similar data we found that these potential confounders attenuated the association between PED and depressive symptoms [44]. To assess whether this association differed by ethnicity, we used the interaction term (PED*Ethnicity). To assess whether ethnic identity, religion, and ethnic social network measures modified the association, we created interaction terms of the psychosocial factor and PED (e.g., religion*PED). SPSS version 21.0 was used for analysis.