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Kurzform der S3-Leitlinie Harnblasenkarzinom

Short version of the German S3 guideline for bladder cancer

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Zusammenfassung

Das Harnblasenkarzinom ist die zweithäufigste urologische Tumorerkrankung. Die S3-Leitlinie Harnblasenkarzinom wurde gemeinsam mit dem Leitlinienprogramm Onkologie der Arbeitsgemeinschaft Medizinisch Wissenschaftlicher Fachgesellschaften e. V. (AWMF), der Deutschen Krebsgesellschaft und der Deutschen Krebshilfe unter Beteiligung von weiteren 31 medizinischen Fachgesellschaften erstellt. Die Kurzversion soll Auszüge an Empfehlungen aus der S3-Leitlinie Blasenkarzinom vorstellen. Die Empfehlungen basieren auf systematischen Literaturrecherchen und Expertenmeinungen und wurden von Blasenkarzinomexperten und Gesellschaften abgestimmt. Die Langversion der S3-Leitlinie Harnblasenkarzinom kann unter dem Link http://leitlinienprogramm-onkologie.de/ eingesehen werden.

Abstract

Urinary bladder cancer is the second most common cancer of the urogenital system. The Guideline Program in Oncology (Leitlinienprogramm Onkologie) of the Association of the Scientific Medical Societies in Germany (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF), the German Cancer Society (Deutsche Krebsgesellschaft) and the German Cancer Aid (Deutsche Krebshilfe) as well as 31 different medical societies have developed the first interdisciplinary, evidence-based German guideline for bladder cancer. This short version presents the resulting series of diagnostic and therapeutic recommendations which were based on a systematic literature search and approved by a team of bladder cancer experts. The full version is available under http://leitlinienprogramm-onkologie.de/.

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Abbreviations

AWMF:

Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e. V.

SIGN:

„Scottish Intercollegiate Guidelines Network“

EK:

Expertenkonsens

NMP22:

Nukleäres Matrixprotein 22

FISH:

Floureszenz-in-situ-Hybridisierung

BTA:

Blasentumorantigen

CT:

Computertomographie

MRT:

Magnetresonanztomographie

TUR-B:

Transuretrale Resektion der Blase

TUR:

Transuretrale Resektion

HAL:

Hexaminolävulinsäure

WL:

Weißlicht

EORTC:

„European Organisation for Research and Treatment of Cancer“

BCG:

Bacille Calmette-Guerin

LK:

Lymphknoten

GC:

Gemcitabin, Cisplatin

MVAC:

Methotrexat, Vinblastin, Doxorubicin und Cisplatin

CR:

„Complete response“

PR:

„Partial response“

AP:

Alkalische Phosphatase

BSC:

„Best supportive care“

PS:

Performancestatus

HR:

Hazard Ratio

KI:

Konfidenzintervall

PD-L1:

„Programed death ligand-1“

NMIBC:

Nicht-muskelinvasives Blasenkarzinom

AUG:

Ausscheidungsurogramm

NICE:

„National Institute for Health and Care Excellence“

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Correspondence to M. Retz.

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M. Retz: Vortragsvergütungen und Honorare von Astellas Pharma GmbH, Janssen-Cilag GmbH, Pfizer GmbH, Bayer AG, Amgen GmbH, Novartis AG und Roche GmbH; J. Gschwend: Vortragsvergütungen und Honorare von Astellas Pharma GmbH, Janssen-Cilag GmbH, Pfizer GmbH, Bayer AG, Amgen GmbH, Novartis AG und Roche GmbH; P. Maisch: Vortragsvergütungen von Pierre-Fabre Pharma GmbH und Reiseunterstützung von Bristol-Myers Squibb.

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Retz, M., Gschwend, J.E. & Maisch, P. Kurzform der S3-Leitlinie Harnblasenkarzinom. Urologe 55, 1173–1187 (2016). https://doi.org/10.1007/s00120-016-0195-1

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