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Operative Therapie des benignen Prostatasyndroms (BPS)

Surgical treatment of male lower urinary tract symptoms (LUTS)

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Zusammenfassung

Die operative Behandlung des benignen Prostatasyndroms umfasst ein großes Spektrum verschiedener Techniken. Dabei gilt die transurethrale Resektion der Prostata (TURP) als Referenzverfahren. In den letzten Jahren traten verschiedene minimal-invasive Behandlungsmodalitäten in den Vordergrund, für die gute kurzfristige funktionelle Ergebnisse beschrieben wurden. Allerdings fehlen Langzeitdaten, um die Effektivität und Sicherheit des jeweiligen Verfahrens nachhaltig beurteilen zu können. Die vorliegende Übersichtsarbeit soll die verschiedenen in Deutschland verfügbaren Therapieoptionen beleuchten und die Datenlage bewerten.

Abstract

Surgical treatment of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO) comprises a variety of treatment modalities. Transurethral resection of the prostate (TURP) is considered the gold standard. In the last decade various new techniques have emerged with encouraging functional results. However, long-term data are missing in order to evaluate the efficacy and safety. This review aims to describe new widely available techniques and to assess the underlying evidence.

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Literatur

  1. Madersbacher S (2012) After three randomised controlled trials comparing 120-W high-performance-system potassium-titanyl-phosphate laser vaporisation to transurethral resection of the prostate (TURP), is this procedure finally first-line, outdated, or still not surpassing TURP? Eur Urol 61:1174–1176

    Article  PubMed  Google Scholar 

  2. Oelke M, Bachmann A, Descazeaud A et al (2012) Guidelines on the Management of Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO). http://www.uroweb.org/gls/pdf/12_Male_LUTS_LR.pdf

  3. Yu X, Elliott SP, Wilt TJ, McBean AM (2008) Practice patterns in benign prostatic hyperplasia surgical therapy: the dramatic increase in minimally invasive technologies. J Urol 180:241–245

    Article  PubMed  Google Scholar 

  4. Malaeb BS, Yu X, McBean AM, Elliott SP (2012) National trends in surgical therapy for benign prostatic hyperplasia in the United States (2000–2008). Urology 79:1111–1117

    Article  PubMed  Google Scholar 

  5. Varkarakis J, Bartsch G, Horninger W (2004) Long-term morbidity and mortality of transurethral prostatectomy: a 10-year follow-up. Prostate 58:248–251

    Article  PubMed  Google Scholar 

  6. Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83:227–237

    Article  PubMed  CAS  Google Scholar 

  7. Reich O, Gratzke C, Bachmann A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249

    Article  PubMed  Google Scholar 

  8. Reich O, Seitz M, Gratzke C et al (2010) Benign prostatic hyperplasia (BPH): surgical therapy options. Urologe A 49:113–126

    Article  PubMed  CAS  Google Scholar 

  9. Faul P, Schlenker B, Gratzke C et al (2008) Clinical and technical aspects of bipolar transurethral prostate resection. Scand J Urol Nephrol 42:318–323

    Article  PubMed  Google Scholar 

  10. Ahyai SA, Gilling P, Kaplan SA et al (2010) Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 58:384–397

    Article  PubMed  Google Scholar 

  11. Zhu G, Xie C, Wang X, Tang X (2012) Bipolar plasmakinetic transurethral resection of prostate in 132 consecutive patients with large gland: three-year follow-up results. Urology 79:397–402

    Article  PubMed  Google Scholar 

  12. Gratzke C, Rehme J, Martens E et al (2012) Long-term results of a prospective single-center trial comparing monopolar and bipolar resection of the prostate with 80 W (KTP) and 120-Watt (HPS)-Laser of the prostate. J Urol 187(4 Suppl):e876

    Article  Google Scholar 

  13. Mamoulakis C, Skolarikos A, Schulze M et al (2012) Results from an international multicentre double-blind randomized controlled trial on the perioperative efficacy and safety of bipolar vs monopolar transurethral resection of the prostate. BJU Int 109:240–248

    Article  PubMed  CAS  Google Scholar 

  14. Seitz M, Bader M, Tilki D et al (2012) Interventional therapies for lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). Minerva Urologica e Nefrologica 64(2):123–133

    PubMed  CAS  Google Scholar 

  15. Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53:382–389

    Article  PubMed  Google Scholar 

  16. Gravas S, Bachmann A, Reich O et al (2011) Critical review of lasers in benign prostatic hyperplasia (BPH). BJU Int 107:1030–1043

    Article  PubMed  Google Scholar 

  17. Bach T, Herrmann TR, Haecker A et al (2009) Thulium:yttrium-aluminium-garnet laser prostatectomy in men with refractory urinary retention. BJU Int 104:361–364

    Article  PubMed  Google Scholar 

  18. Fu WJ, Hong BF, Yang Y et al (2009) Vaporesection for managing benign prostatic hyperplasia using a 2-microm continuous-wave laser: a prospective trial with 1-year follow-up. BJU Int 103:352–356

    Article  PubMed  Google Scholar 

  19. Netsch C, Bach T, Pohlmann L et al (2012) Comparison of 120-200 W 2 μm thulium:yttrium-aluminum-garnet vapoenucleation of the prostate. J Endourol 26:224–229

    Article  PubMed  Google Scholar 

  20. Zhang F, Shao Q, Herrmann TR et al (2012) Thulium laser versus holmium laser transurethral enucleation of the prostate: 18-month follow-up data of a single center. Urology 79:869–874

    Article  PubMed  Google Scholar 

  21. Capitan C, Blazquez C, Martin MD et al (2011) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: a randomized clinical trial with 2-year follow-up. Eur Urol 60:734–739

    Article  PubMed  Google Scholar 

  22. Al-Ansari A, Younes N, Sampige VP et al (2010) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 58:349–355

    Article  PubMed  Google Scholar 

  23. Bachmann A, Muir GH, Collins EJ et al (2012) 180-W XPS GreenLight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61:600–607

    Article  PubMed  Google Scholar 

  24. Lukacs B, Loeffler J, Bruyere F et al (2012) Photoselective vaporization of the prostate with greenlight 120-W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial. Eur Urol 61:1165–1173

    Article  PubMed  Google Scholar 

  25. Bachmann A, Muir GH, Collins EJ et al (2012) 180-W XPS greenlight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61(3):600–607

    Article  PubMed  Google Scholar 

  26. Hamann MF, Naumann CM, Seif C et al (2008) Functional outcome following photoselective vaporisation of the prostate (PVP): urodynamic findings within 12 months follow-up. Eur Urol 54:902–907

    Article  PubMed  Google Scholar 

  27. Vogel A, Venugopalan V (2003) Mechanisms of pulsed laser ablation of biological tissues. Chem Rev 103:577–644

    Article  PubMed  CAS  Google Scholar 

  28. Seitz M, Ruszat R, Bayer T et al (2009) Ex vivo and in vivo investigations of the novel 1,470 nm diode laser for potential treatment of benign prostatic enlargement. Lasers Med Sci 24:419–424

    Article  PubMed  Google Scholar 

  29. Seitz M, Sroka R, Gratzke C et al (2007) The diode laser: a novel side-firing approach for laser vaporisation of the human prostate – immediate efficacy and 1-year follow-up. Eur Urol 52:1717–1722

    Article  PubMed  Google Scholar 

  30. Lusuardi L, Myatt A, Sieberer M et al (2011) Safety and efficacy of Eraser laser enucleation of the prostate: preliminary report. J Urol 186:1967–1971

    Article  PubMed  Google Scholar 

  31. Ruszat R, Seitz M, Wyler SF et al (2008) GreenLight laser vaporization of the prostate: single-center experience and long-term results after 500 procedures. Eur Urol 54:893–901

    Article  PubMed  Google Scholar 

  32. Reich O, Schlenker B, Gratzke C et al (2010) Plasma vaporisation of the prostate: initial clinical results. Eur Urol 57(4):693–697

    Article  PubMed  Google Scholar 

  33. Geavlete B, Georgescu D, Multescu R et al (2012) Bipolar plasma vaporization vs monopolar and bipolar TURP – a prospective, randomized, long-term comparison. Urology 78:930–935

    Article  Google Scholar 

  34. Berges R, Dreikorn K, Hofner K et al (2009) Therapy of benign prostate syndrome (BPS): guidelines of the German Urologists (DGU). Urologe A 48:1503–1516

    Article  PubMed  CAS  Google Scholar 

  35. Hargreave TB, Heynes CF, Kendrick SW et al (1996) Mortality after transurethral and open prostatectomy in Scotland. Br J Urol 77:547–553

    Article  PubMed  CAS  Google Scholar 

  36. Gratzke C, Schlenker B, Seitz M et al (2007) Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 177:1419–1422

    Article  PubMed  Google Scholar 

  37. Oktay B, Koc G, Vuruskan H et al (2011) Laparoscopic extraperitoneal simple prostatectomy for benign prostate hyperplasia: a two-year experience. Urol J 8:107–112

    PubMed  Google Scholar 

  38. Lee JY, Kang DH, Chung JH et al (2012) Laparoendoscopic single-site surgery for benign urologic disease with a homemade single port device: design and tips for beginners. Korean J Urol 53:165–170

    Article  PubMed  Google Scholar 

  39. Sutherland DE, Perez DS, Weeks DC (2011) Robot-assisted simple prostatectomy for severe benign prostatic hyperplasia. J Endourol 25:641–644

    Article  PubMed  Google Scholar 

  40. Sotelo RJ, Astigueta JC, Desai MM et al (2009) Laparoendoscopic single-site surgery simple prostatectomy: initial report. Urology 74:626–630

    Article  PubMed  Google Scholar 

  41. Tooher R, Sutherland P, Costello A et al (2004) A systematic review of holmium laser prostatectomy for benign prostatic hyperplasia. J Urol 171:1773–1781

    Article  PubMed  Google Scholar 

  42. Chapple CR, Issa MM, Woo H (1999) Transurethral needle ablation (TUNA). A critical review of radiofrequency thermal therapy in the management of benign prostatic hyperplasia. Eur Urol 35:119–128

    Article  PubMed  CAS  Google Scholar 

  43. Boyle P, Robertson C, Vaughan ED, Fitzpatrick JM (2004) A meta-analysis of trials of transurethral needle ablation for treating symptomatic benign prostatic hyperplasia. BJU Int 94:83–88

    Article  PubMed  Google Scholar 

  44. Berges R, Dreikorn K, Hofner K et al (2009) Therapy of benign prostate syndrome (BPS): guidelines of the German Urologists (DGU). Urologe A 48(11):1356–1360

    Article  PubMed  CAS  Google Scholar 

  45. Chin PT, Bolton DM, Jack G et al (2012) Prostatic urethral lift: two-year results after treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia. Urology 79:5–11

    Article  PubMed  Google Scholar 

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Der korrespondierende Autor weist für sich und seine Koautoren auf folgende Beziehungen hin: Vorträge für AMS.

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Gratzke, C., Strittmatter, F., Reich, O. et al. Operative Therapie des benignen Prostatasyndroms (BPS). Urologe 51, 1297–1307 (2012). https://doi.org/10.1007/s00120-012-2959-6

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  • DOI: https://doi.org/10.1007/s00120-012-2959-6

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