Zusammenfassung
Die operative Behandlung des benignen Prostatasyndroms umfasst ein großes Spektrum verschiedener Techniken. Dabei gilt die transurethrale Resektion der Prostata (TURP) als Referenzverfahren. In den letzten Jahren traten verschiedene minimal-invasive Behandlungsmodalitäten in den Vordergrund, für die gute kurzfristige funktionelle Ergebnisse beschrieben wurden. Allerdings fehlen Langzeitdaten, um die Effektivität und Sicherheit des jeweiligen Verfahrens nachhaltig beurteilen zu können. Die vorliegende Übersichtsarbeit soll die verschiedenen in Deutschland verfügbaren Therapieoptionen beleuchten und die Datenlage bewerten.
Abstract
Surgical treatment of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO) comprises a variety of treatment modalities. Transurethral resection of the prostate (TURP) is considered the gold standard. In the last decade various new techniques have emerged with encouraging functional results. However, long-term data are missing in order to evaluate the efficacy and safety. This review aims to describe new widely available techniques and to assess the underlying evidence.
Literatur
Madersbacher S (2012) After three randomised controlled trials comparing 120-W high-performance-system potassium-titanyl-phosphate laser vaporisation to transurethral resection of the prostate (TURP), is this procedure finally first-line, outdated, or still not surpassing TURP? Eur Urol 61:1174–1176
Oelke M, Bachmann A, Descazeaud A et al (2012) Guidelines on the Management of Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO). http://www.uroweb.org/gls/pdf/12_Male_LUTS_LR.pdf
Yu X, Elliott SP, Wilt TJ, McBean AM (2008) Practice patterns in benign prostatic hyperplasia surgical therapy: the dramatic increase in minimally invasive technologies. J Urol 180:241–245
Malaeb BS, Yu X, McBean AM, Elliott SP (2012) National trends in surgical therapy for benign prostatic hyperplasia in the United States (2000–2008). Urology 79:1111–1117
Varkarakis J, Bartsch G, Horninger W (2004) Long-term morbidity and mortality of transurethral prostatectomy: a 10-year follow-up. Prostate 58:248–251
Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83:227–237
Reich O, Gratzke C, Bachmann A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249
Reich O, Seitz M, Gratzke C et al (2010) Benign prostatic hyperplasia (BPH): surgical therapy options. Urologe A 49:113–126
Faul P, Schlenker B, Gratzke C et al (2008) Clinical and technical aspects of bipolar transurethral prostate resection. Scand J Urol Nephrol 42:318–323
Ahyai SA, Gilling P, Kaplan SA et al (2010) Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 58:384–397
Zhu G, Xie C, Wang X, Tang X (2012) Bipolar plasmakinetic transurethral resection of prostate in 132 consecutive patients with large gland: three-year follow-up results. Urology 79:397–402
Gratzke C, Rehme J, Martens E et al (2012) Long-term results of a prospective single-center trial comparing monopolar and bipolar resection of the prostate with 80 W (KTP) and 120-Watt (HPS)-Laser of the prostate. J Urol 187(4 Suppl):e876
Mamoulakis C, Skolarikos A, Schulze M et al (2012) Results from an international multicentre double-blind randomized controlled trial on the perioperative efficacy and safety of bipolar vs monopolar transurethral resection of the prostate. BJU Int 109:240–248
Seitz M, Bader M, Tilki D et al (2012) Interventional therapies for lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). Minerva Urologica e Nefrologica 64(2):123–133
Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53:382–389
Gravas S, Bachmann A, Reich O et al (2011) Critical review of lasers in benign prostatic hyperplasia (BPH). BJU Int 107:1030–1043
Bach T, Herrmann TR, Haecker A et al (2009) Thulium:yttrium-aluminium-garnet laser prostatectomy in men with refractory urinary retention. BJU Int 104:361–364
Fu WJ, Hong BF, Yang Y et al (2009) Vaporesection for managing benign prostatic hyperplasia using a 2-microm continuous-wave laser: a prospective trial with 1-year follow-up. BJU Int 103:352–356
Netsch C, Bach T, Pohlmann L et al (2012) Comparison of 120-200 W 2 μm thulium:yttrium-aluminum-garnet vapoenucleation of the prostate. J Endourol 26:224–229
Zhang F, Shao Q, Herrmann TR et al (2012) Thulium laser versus holmium laser transurethral enucleation of the prostate: 18-month follow-up data of a single center. Urology 79:869–874
Capitan C, Blazquez C, Martin MD et al (2011) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: a randomized clinical trial with 2-year follow-up. Eur Urol 60:734–739
Al-Ansari A, Younes N, Sampige VP et al (2010) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 58:349–355
Bachmann A, Muir GH, Collins EJ et al (2012) 180-W XPS GreenLight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61:600–607
Lukacs B, Loeffler J, Bruyere F et al (2012) Photoselective vaporization of the prostate with greenlight 120-W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial. Eur Urol 61:1165–1173
Bachmann A, Muir GH, Collins EJ et al (2012) 180-W XPS greenlight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61(3):600–607
Hamann MF, Naumann CM, Seif C et al (2008) Functional outcome following photoselective vaporisation of the prostate (PVP): urodynamic findings within 12 months follow-up. Eur Urol 54:902–907
Vogel A, Venugopalan V (2003) Mechanisms of pulsed laser ablation of biological tissues. Chem Rev 103:577–644
Seitz M, Ruszat R, Bayer T et al (2009) Ex vivo and in vivo investigations of the novel 1,470 nm diode laser for potential treatment of benign prostatic enlargement. Lasers Med Sci 24:419–424
Seitz M, Sroka R, Gratzke C et al (2007) The diode laser: a novel side-firing approach for laser vaporisation of the human prostate – immediate efficacy and 1-year follow-up. Eur Urol 52:1717–1722
Lusuardi L, Myatt A, Sieberer M et al (2011) Safety and efficacy of Eraser laser enucleation of the prostate: preliminary report. J Urol 186:1967–1971
Ruszat R, Seitz M, Wyler SF et al (2008) GreenLight laser vaporization of the prostate: single-center experience and long-term results after 500 procedures. Eur Urol 54:893–901
Reich O, Schlenker B, Gratzke C et al (2010) Plasma vaporisation of the prostate: initial clinical results. Eur Urol 57(4):693–697
Geavlete B, Georgescu D, Multescu R et al (2012) Bipolar plasma vaporization vs monopolar and bipolar TURP – a prospective, randomized, long-term comparison. Urology 78:930–935
Berges R, Dreikorn K, Hofner K et al (2009) Therapy of benign prostate syndrome (BPS): guidelines of the German Urologists (DGU). Urologe A 48:1503–1516
Hargreave TB, Heynes CF, Kendrick SW et al (1996) Mortality after transurethral and open prostatectomy in Scotland. Br J Urol 77:547–553
Gratzke C, Schlenker B, Seitz M et al (2007) Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 177:1419–1422
Oktay B, Koc G, Vuruskan H et al (2011) Laparoscopic extraperitoneal simple prostatectomy for benign prostate hyperplasia: a two-year experience. Urol J 8:107–112
Lee JY, Kang DH, Chung JH et al (2012) Laparoendoscopic single-site surgery for benign urologic disease with a homemade single port device: design and tips for beginners. Korean J Urol 53:165–170
Sutherland DE, Perez DS, Weeks DC (2011) Robot-assisted simple prostatectomy for severe benign prostatic hyperplasia. J Endourol 25:641–644
Sotelo RJ, Astigueta JC, Desai MM et al (2009) Laparoendoscopic single-site surgery simple prostatectomy: initial report. Urology 74:626–630
Tooher R, Sutherland P, Costello A et al (2004) A systematic review of holmium laser prostatectomy for benign prostatic hyperplasia. J Urol 171:1773–1781
Chapple CR, Issa MM, Woo H (1999) Transurethral needle ablation (TUNA). A critical review of radiofrequency thermal therapy in the management of benign prostatic hyperplasia. Eur Urol 35:119–128
Boyle P, Robertson C, Vaughan ED, Fitzpatrick JM (2004) A meta-analysis of trials of transurethral needle ablation for treating symptomatic benign prostatic hyperplasia. BJU Int 94:83–88
Berges R, Dreikorn K, Hofner K et al (2009) Therapy of benign prostate syndrome (BPS): guidelines of the German Urologists (DGU). Urologe A 48(11):1356–1360
Chin PT, Bolton DM, Jack G et al (2012) Prostatic urethral lift: two-year results after treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia. Urology 79:5–11
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Gratzke, C., Strittmatter, F., Reich, O. et al. Operative Therapie des benignen Prostatasyndroms (BPS). Urologe 51, 1297–1307 (2012). https://doi.org/10.1007/s00120-012-2959-6
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DOI: https://doi.org/10.1007/s00120-012-2959-6
Schlüsselwörter
- Benignes Prostatasyndrom (BPS)
- Benigne Prostatahyperplasie (BPH)
- Transurethrale Resektion der Prostata (TURP)
- Offene Adenomenukleation
- Photoselektive Laservaporisation der Prostata (PVP)