Zusammenfassung
In den letzten Jahren wurden aufgrund der verbesserten Hard- und Software moderner MR-Geräte große Fortschritte in der magnetresonanztomographischen Bildgebung von Pankreastumoren erzielt. Trotz dieser Verbesserungen ist die Multislice-CT (MSCT) weiterhin in den meisten Praxen und Kliniken das bevorzugte Verfahren zur Diagnostik von Pankreastumoren, weil damit die wesentlichen Fragen des Klinikers mit einer hohen Treffsicherheit beantwortet werden können. In unklaren Fällen jedoch kann die „State-of-the-art“-durchgeführte MRT die zur Diagnosestellung relevanten Zusatzinformationen liefern und damit das optimale Therapiekonzept ermöglichen. Die vorliegende Arbeit gibt einen Überblick über die Einsatzmöglichkeiten der MRT zur Diagnostik maligner Pankreastumoren.
Abstract
In recent years continuous advancements in software and hardware technology of modern MRI systems have contributed to substantial progress in the field of pancreatic tumor imaging. Despite technical advances in abdominal MRI, multislice CT still remains the preferential diagnostic tool for pancreatic lesions. In the majority of cases the essential clinical questions can thereby be answered with a high degree of accuracy. However, in dilemma cases state-of-the-art MR imaging can provide relevant information for the diagnosis allowing an optimal therapeutic concept. This report gives an overview on possible applications for MRI in the diagnostic evaluation of malignant pancreatic tumors.
Literatur
Lee SS, Byun JH, Park BJ et al (2008) Quantitative analysis of diffusion-weighted magnetic resonance imaging of the pancreas: usefulness in characterizing solid pancreatic masses. J Magn Reson Imaging 28(4):928–936
Song SJ, Lee JM, Kim YJ et al (2007) Differentiation of intraductal papillary mucinous neoplasms from other pancreatic cystic masses: comparison of multirow-detector CT and MR imaging using ROC analysis. J Magn Reson Imaging 26(1):86–93
Kim JK, Altun E, Elias J Jr et al (2007) Focal pancreatic mass: distinction of pancreatic cancer from chronic pancreatitis using gadolinium-enhanced 3D-gradient-echo MRI. J Magn Reson Imaging 26(2):313–322
Semelka RC, Custodio CM, Cem Balci N, Woosley JT (2000) Neuroendocrine tumors of the pancreas: spectrum of appearances on MRI. J Magn Reson Imaging 11(2):141–148
Schneider G, Siveke JT, Eckel F, Schmid RM (2005) Pancreatic cancer: basic and clinical aspects. Gastroenterology 128(6):1606–1625
Balci NC, Semelka RC (2001) Radiologic diagnosis and staging of pancreatic ductal adenocarcinoma. Eur J Radiol 38(2):105–112
Balci NC, Semelka RC (2001) Radiologic features of cystic, endocrine and other pancreatic neoplasms. Eur J Radiol 38(2):113–119
Lee JH, Yu JS, Kim H et al (2008) Solid pseudopapillary carcinoma of the pancreas: differentiation from benign solid pseudopapillary tumour using CT and MRI. Clin Radiol 63(9):1006–1014
Reiser-Erkan C, Gaa J, Kleeff J (2008) Pancreatic cancer with lymph node metastasis and perineural invasion of the celiac trunk. Clin Gastroenterol Hepatol, in press
Bruegel M, Holzapfel K, Gaa J et al (2008) Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique. Eur Radiol 18(3):477–485
Bruegel M, Gaa J, Waldt S (2008) Diagnosis of hepatic metastasis: comparison of respiration-triggered diffusion-weighted echo-planar MRI and five T2-weighted turbo spin-echo sequences. AJR Am J Roentgenol 191(5):1421–1429
Kalra MK, Maher MM, Mueller PR, Saini S (2003) State-of-the-art imaging of pancreatic neoplasms. Br J Radiol 76(912):857-865
Trede M, Rumstadt B, Wendl K et al (1997) Ultrafast magnetic resonance imaging improves the staging of pancreatic tumors. Ann Surg 226(4):393–405 (discussion 405–407)
Fischer U, Vosshenrich R, Horstmann O et al (2002) Preoperative local MRI-staging of patients with a suspected pancreatic mass. Eur Radiol 12(2):296–303
Matsuki M, Inada Y, Nakai G et al (2007) Diffusion-weighed MR imaging of pancreatic carcinoma. Abdom Imaging 32(4):481–483
Lopez Hänninen E, Amthauer H, Hosten N et al (2002) Prospective evaluation of pancreatic tumors: accuracy of MR imaging with MR cholangiopancreatography and MR angiography. Radiology 224(1):34–41
Procacci C, Megibow AJ, Carbognin G et al (1999) Intraductal papillary mucinous tumor of the pancreas: a pictorial essay. Radiographics 19(6):1447–1463
Lim JH, Lee G, Oh YL (2001) Radiologic spectrum of intraductal papillary mucinous tumor of the pancreas. Radiographics 21(2):323–337 (discussion 337–340)
Schima W, Függer R, Schober E et al (2002) Diagnosis and staging of pancreatic cancer: comparison of mangafodipir trisodium-enhanced MR imaging and contrast-enhanced helical hydro-CT. AJR Am J Roentgenol 179(3):717–724
Crippa S, Salvia R, Warshaw AL et al (2008) Mucinous cystic neoplasm of the pancreas is not an aggressive entity: lessons from 163 resected patients. Ann Surg 247(4):571–579
Warshaw AL, Compton CC, Lewandrowski K et al (1990) Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg 212(4):432–443
Sohn TA, Yeo CJ, Cameron JL et al (2004) Intraductal papillary mucinous neoplasms of the pancreas: an updated experience. Ann Surg 239(6):788–797
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gaa, J., Fingerle, A., Holzapfel, K. et al. MRT bei malignen Pankreastumoren. Radiologe 49, 124–130 (2009). https://doi.org/10.1007/s00117-008-1757-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00117-008-1757-z
Schlüsselwörter
- Pankreastumor
- Zystische Pankreastumoren
- Magnetresonanz-Cholangiopankreatikographie (MRCP)
- Magnetresonanztomographie (MRT)
- Diffusionsgewichtete MRT (DWI)