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Gastrointestinale Störungen bei hyperkinetischen Bewegungsstörungen und Ataxien

Gastrointestinal disorders in hyperkinetic movement disorders and ataxia

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Zusammenfassung

Störungen des Gastrointestinaltraktes sind bei Patient*innen mit hypokinetischen Bewegungsstörungen und insbesondere der Parkinson-Krankheit Gegenstand einer zunehmend intensiveren neuromedizinischen Forschung. Bei Patient*innen mit hyperkinetischen Bewegungsstörungen und Ataxien gibt es bislang weniger verfügbare Daten. Der vorliegende Artikel fasst die vorhandenen und relevanten Publikationen zu diesem Thema übersichtsartig zusammen. Besonders im Fokus stehen dabei der essenzielle Tremor, das Restless-legs-Syndrom, der Morbus Huntington sowie die Gruppe der hereditären Ataxien. Zukünftige Forschung ist notwendig, um auch bei diesen Krankheitsbildern detaillierte Informationen zu möglichen spezifischen Störungsmustern, den zugrunde liegenden Pathomechanismen sowie den daraus abzuleitenden Therapieansätzen zu erlangen.

Abstract

Disorders of the gastrointestinal tract in patients suffering from hypokinetic movement disorders, and in particular Parkinson’s disease, have increasingly been the subject of more intensive neuromedical research. So far, few data are available for patients with hyperkinetic movement disorders and ataxias. This review article summarizes the currently available and relevant publications on this topic. The particular focus is on essential tremor, restless legs syndrome, Huntington’s disease and the group of hereditary ataxias. Further intensive research will be necessary in the future to collect detailed information also for these disease symptoms about specific disturbance patterns, in order to understand the underlying pathological pathways and to derive specific treatment approaches.

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Authors and Affiliations

  1. Klinik für Neurologie mit Institut für Translationale Neurologie, Parkinsonzentrum Münster-Osnabrück (PAMOS), Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland

    Inga Claus

  2. Klinik für Neurologie und Neurologische Frührehabilitation, Parkinsonzentrum Münster-Osnabrück (PAMOS), Klinikum Osnabrück, Am Finkenhügel 1, 49076, Osnabrück, Deutschland

    Tobias Warnecke

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  1. Inga Claus
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  2. Tobias Warnecke
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Correspondence to Inga Claus or Tobias Warnecke.

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Interessenkonflikt

I. Claus und T. Warnecke geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Claus, I., Warnecke, T. Gastrointestinale Störungen bei hyperkinetischen Bewegungsstörungen und Ataxien. Nervenarzt (2024). https://doi.org/10.1007/s00115-024-01655-z

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  • DOI: https://doi.org/10.1007/s00115-024-01655-z

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