Abstract
We investigated, retrospectively, the prevalence of gastroesophageal inflammation in patients with Huntington’s disease (HD) during 10 years in our center. We found a high prevalence of gastritis or esophagitis even in patients without complaints, indicating that gastrointestinal disease is more common in HD than patients’ complaints. There was no correlation with motor disturbances but with the duration and severity of HD. Influences from the disease itself as well as secondary mechanisms like malnutrition, medication and general disability may contribute.
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The local ethics committee of the university approved this study.
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The author(s) declare that they have no competing interests.
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J. E. Andrich and M. Wobben contributed equally to this work.
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Andrich, J.E., Wobben, M., Klotz, P. et al. Upper gastrointestinal findings in Huntington’s disease: patients suffer but do not complain. J Neural Transm 116, 1607–1611 (2009). https://doi.org/10.1007/s00702-009-0310-1
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DOI: https://doi.org/10.1007/s00702-009-0310-1