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Hämangiome

Glukokortikoid- und Interferontherapie

  • Hämangiome
  • Published:
Monatsschrift Kinderheilkunde Aims and scope Submit manuscript

Zusammenfassung

Hämangiome zählen mit einem Auftreten von bis zu 10% zu den häufigsten gutartigen Tumoren im Kindesalter. Sie sind charakterisiert durch ein aggressives Wachstum während der ersten Lebensmonate (Proliferationsphase), gefolgt von einer allmählichen Regression (Involutionsphase) bis zur völligen Abheilung bei 90% der Patienten im Alter von 10–12 Jahren (Endstadium). Aufgrund des natürlichen Tumorverlaufs ist in der Regel eine abwartende Haltung indiziert. Bei einer Beeinträchtigung vitaler Funktionen durch den Tumor stehen neben Kryo-, Laser- oder operativer Therapie die systemische Therapie mit Glukokortikoiden (GK) oder Interferon zur Verfügung.

Abstract

Hemangiomas are the most common tumor in childhood (frequency up to 10%). They show a characteristic natural history of rapid proliferation and slow spontaneous involution. Only minor skin changes remain after regression in the vast majority of cases. Thus, treatment seems inappropriate in most patients. However, in rare instances, hemangiomas can be function or life threatening. Hemangiomas, which do not show improvement after surgery, cryotherapy, or laser therapy, require treatment with either corticosteroids or interferon.

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Notes

  1. Die in runden Klammern angegebenen Zahlen beziehen sich auf eine Studie von Blei u. Chianese [4], bei der 30 Kinder mit 2–4 mg/kg×Tag Prednison/Prednisolon behandelt und auf Nebenwirkungen untersucht wurden

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Authors and Affiliations

  1. Kinderklinik und Kinderpoliklinik, Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität München

    A. Schweiger-Kabesch, M. Deml, K. Kurnik, B. Kammer & H. Schmidt

  2. Kinderklinik und Kinderpoliklinik, Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität, Lindwurmstraße 4, 80337, München

    A. Schweiger-Kabesch

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  1. A. Schweiger-Kabesch
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  2. M. Deml
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  3. K. Kurnik
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  4. B. Kammer
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Correspondence to A. Schweiger-Kabesch.

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Schweiger-Kabesch, A., Deml, M., Kurnik, K. et al. Hämangiome. Monatsschr Kinderheilkd 152, 29–37 (2004). https://doi.org/10.1007/s00112-003-0870-3

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  • DOI: https://doi.org/10.1007/s00112-003-0870-3

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