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Hautinfektionen nach Transplantation

Skin infections after transplantation

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Zusammenfassung

Hautinfektionen bei organtransplantierten Patienten sind sehr häufig und von hoher Priorität, weil nicht selten schwere Krankheitsbilder beobachtet werden. Im Vordergrund stehen bakterielle, mykotische und virale Infektionen, wobei das Infektionsrisiko mit der Dauer der Immunsuppression steigt. Insbesondere findet man Pyodermien, Infektionen mit Herpesviren 6/7, Herpes-simplex- und Varicella-Zoster-Virus-Reaktivierung, Zytomegalie-Virusinfektionen und Candida-Infektionen. Auch seltene Erreger müssen in Betracht gezogen werden. Die infektiösen Hautmanifestationen lassen sich in den ersten Jahren post transplantationem in 3 Phasen einordnen. Diagnose und frühzeitige Therapie, zusammen mit Prophylaxe und Nachsorgebetreuung der Patienten müssen angestrebt werden, um lebensbedrohliche Komplikationen zu vermeiden.

Abstract

Skin infections after transplantation are frequent and of special importance because they may be quite severe. The spectrum of dermatologic infections in transplant recipients includes bacterial, mycotic and viral diseases. Pyoderma, herpes virus 6/7, herpes simplex virus, varicella-zoster virus, cytomegalovirus and candida infections predominate. Rare pathogens must be also considered. Cutaneous infections can be divided into three phases following transplantation. Diagnosis and adequate early therapy together with specific prophylaxis and follow-up of transplant patients should be strived for to avoid life-threatening complications.

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Literatur

  1. Dicle O, Parmaksizoglu B, Gurkan A et al (2009) Skin infections in 401 renal transplant recipients in Southern Turkey. Exp Clin Transplant 2:133–136

    Google Scholar 

  2. Hogewoning AA, Goettsch W, Loveren H van et al (2001) Skin infections in renal transplant recipients. Clin Transplant 15:32–38

    Article  CAS  PubMed  Google Scholar 

  3. Kaisar MO, Kirwan RM, Strutton GM et al (2008) Cutaneous manifestations of cytomegalovirus disease in renal transplant recipients: a case series. Transpl Infect Dis 10:209–213

    Article  CAS  PubMed  Google Scholar 

  4. Kern WV, Wagner D, Hirsch HH (2005) Infektionen nach Organtransplantation. Internist 46:630–642

    Article  CAS  PubMed  Google Scholar 

  5. Kidney disease: Improving Global Outcomes (KDIGO), Transplant Work Group (2009) KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant 9(Suppl 3):S1–S157

    Google Scholar 

  6. Kotton CN (2008) Skin and soft tissue infections in the transplant population. Curr Infect Dis Rep 10:387–393

    Article  PubMed  Google Scholar 

  7. Lanuti EL, Keegan BR, Wolf IH et al (2009) Dermatological complications in transplant patients and composite tissue allotransplant pathology. In: Ruiz P (ed) Transplantation pathology. Cambridge University Press, New York, pp 26–44

  8. Miele PS, Levy CS, Smith MA et al (2002) Primary cutaneous fungal infections in solid organ transplantation: a case series. Am J Transplant 2:678–683

    Article  PubMed  Google Scholar 

  9. Miller GG, Dummer JS (2007) Herpes simplex and varicella zoster virus: forgotten but not gone. Am J Transplant 7:741–747

    Article  CAS  PubMed  Google Scholar 

  10. Ramos A, Ussetti P, Laporta R et al (2009) Cutaneous aspergillosis in a lung transplant recipient. Transpl Infect Dis 11:471–473

    Article  CAS  PubMed  Google Scholar 

  11. Schmied E, Dufour JF, Euvrard S (2004) Nontumoral dermatologic problems after liver transplantation. Liver Transpl 10:331–339

    Article  PubMed  Google Scholar 

  12. Ulrich C, Hackenthal M, Meyer T et al (2008) Hautinfektionen bei organtransplantierten Patienten. J Dtsch Dermatol Ges 6:98–105

    Article  PubMed  Google Scholar 

  13. Wisgerhof HC, Edelbroek JR, Fijter JW de et al (2009) Trends of skin diseases in organ transplant recipients transplanted between 1966 and 2006: a cohort study with follow-up between 1994 and 2006. Br J Dermatol (in press)

  14. Zorman JV, Zupanc TL, Parač Z et al (2009) Primary cutaneous cryptococcosis in a renal transplant recipient: case report. Mycoses (in press)

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Correspondence to I.H. Wolf.

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Wolf, I. Hautinfektionen nach Transplantation. Hautarzt 61, 230–233 (2010). https://doi.org/10.1007/s00105-009-1859-1

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