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Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3)

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Summary

A chromosome 13 deletion in a patient with sporadic retinoblastoma appears to have separated the loci for retinoblastoma and esterase D. This study indicates that: (1) the retinoblastoma locus is distinct from the esterase D locus; and (2) the linear order of these genes is centromere-esterase D-retinoblastoma.

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Authors and Affiliations

  1. Division of Medical Genetics, Department of Medicine, UCLA School of Medicine, Los Angeles

    Robert S. Sparkes & Maryellen C. Sparkes

  2. Department of Pediatrics, UCLA School of Medicine, Los Angeles

    Robert S. Sparkes & Maryellen C. Sparkes

  3. Department of Psychiatry, UCLA School of Medicine, Los Angeles

    Robert S. Sparkes & Maryellen C. Sparkes

  4. Center for the Health Sciences, Los Angeles

    Robert S. Sparkes & Maryellen C. Sparkes

  5. Department of Ophthalmology, University of Washington School of Medicine, Seattle, USA

    Robert E. Kalina & Roberta A. Pagon

  6. Department of Pediatrics, University of Washington School of Medicine, Seattle, USA

    Roberta A. Pagon & Darrell J. Salk

  7. Department of Pathology, University of Washington School of Medicine, Seattle, USA

    Darrell J. Salk & Christine M. Disteche

  8. Childrens Orthopedic Hospital and Medical Center, Seattle, USA

    Darrell J. Salk & Christine M. Disteche

Authors
  1. Robert S. Sparkes
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  2. Maryellen C. Sparkes
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  3. Robert E. Kalina
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  4. Roberta A. Pagon
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  5. Darrell J. Salk
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  6. Christine M. Disteche
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Sparkes, R.S., Sparkes, M.C., Kalina, R.E. et al. Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3). Hum Genet 68, 258–259 (1984). https://doi.org/10.1007/BF00418397

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  • DOI: https://doi.org/10.1007/BF00418397

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