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Singlet Oxygen Quantum Yield Determination for a Fluorene-Based Two-Photon Photosensitizer

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The quantum yield, ΦΔ, of singlet oxygen generation under two-photon excitation has been determined for a fluorene derivative. A photochemical method was developed using 1,3-diphenylisobenzofuran (DPBF), a chemical quencher of 1O2, and 2-(9,9-didecyl-7-nitrofluoren-2-yl)benzothiazole (1) as a two-photon photosensitizer (PS). The photochemical kinetics of the quencher was measured by two different fluorescence methods. Fluorene 1 exhibited relatively high singlet oxygen quantum yield, ΦΔ ≈ 0.4 ± 0.1, and had a two-photon absorption cross-section of 28 ± 5 GM. Thus, 1 may have potential for use as a two-photon PS in the near-IR spectral region for biomedical applications.

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ACKNOWLEDGMENTS

We wish to acknowledge the Civilian Research and Development Foundation (UK-C2-2574-MO-04), the donors of The Petroleum Research Fund of the American Chemical Society, the Research Corporation Cottrell College Science program, the National Research Council COBASE award, the Florida Hospital Gala Endowed Program for Oncologic Research, the National Science Foundation, and the University of Central Florida Presidential Initiative for Major Research Equipment for partial support of this work. The authors also wish to thank Dr. Joel M. Hales and Ms. Mihaela Balu for assistance in two-photon absorption measurements.

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  1. Department of Chemistry and College of Optics and Photonics, CREOL and FPCE, University of Central Florida, P.O. Box 162366, Orlando, Florida, 32816-2366, USA

    Kevin D. Belfield

  2. Institute of Physics, Prospect Nauki, 46 Kiev-28, 03028, Kiev, Ukraine

    Kevin D. Belfield, Mykhailo V. Bondar & Olga V. Przhonska

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  1. Kevin D. Belfield
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  2. Mykhailo V. Bondar
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  3. Olga V. Przhonska
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Correspondence to Kevin D. Belfield.

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Belfield, K.D., Bondar, M.V. & Przhonska, O.V. Singlet Oxygen Quantum Yield Determination for a Fluorene-Based Two-Photon Photosensitizer. J Fluoresc 16, 111–117 (2006). https://doi.org/10.1007/PL00021939

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