Skip to main content
Log in

Antithyroid drug treatment prior to radioiodine therapy for Graves’ disease: Yes or no?

  • Opinion
  • Published:
Journal of Endocrinological Investigation Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Wartofsky L. Radioiodine therapy for Graves’ disease: case selection and restrictions recommended to patients in North America. Thyroid 1997, 7: 213–216.

    Article  PubMed  CAS  Google Scholar 

  2. Solomon B., Glinoer D., Lagasse R., Wartofsky L. Current trends in the management of Graves’ disease. J. Clin. Endocrinol. Metab. 1990, 70: 1518–1524.

    Article  PubMed  CAS  Google Scholar 

  3. Kadmon M., Noto R.B., Boney C.M., Goodwin G., Gruppuso P.A. Thyroid storm in a child following radioactive iodine (RAI) therapy: a consequence of RAI versus withdrawal of antithyroid medication. J. Clin. Endocrinol. Metab. 2001, 86: 1865–1867.

    Article  PubMed  CAS  Google Scholar 

  4. Burch H.B., Solomon B.L., Cooper D.S., Ferguson P., Walpert N., Howard R. The effect of antithyroid drug pre-treatment on acute changes in thyroid hormone levels after 131I ablation for Graves’ disease. J. Clin. Endocrinol. Metab. 2001, 86: 3016–3021.

    PubMed  CAS  Google Scholar 

  5. Bogazzi F., Bartalena L., Brogioni S. et al. Comparison of radioiodine with radioiodine plus lithium in the treatment of Graves’ hyperthyroidism. J. Clin. Endocrinol. Metab. 1999, 84: 499–503.

    PubMed  CAS  Google Scholar 

  6. Bogazzi F., Bartalena L., Campomori A. et al. Treatment with lithium prevents serum thyroid hormone increase after thionamide withdrawal and radioiodine therapy in patients with Graves’ disease. J. Clin. Endocrinol. Metab. 2002, 87: 4490–4495.

    Article  PubMed  CAS  Google Scholar 

  7. Lazarus J.H. 1998 Is thyroxine during lithium therapy necessary? J. Endocrinol. Invest. 1998, 21: 784–786.

    Article  PubMed  CAS  Google Scholar 

  8. Bartalena L., Bogazzi F., Martino E. Is thyroxine during lithium therapy necessary? J. Endocrinol. Invest. 1999, 22: 220–222.

    Article  PubMed  CAS  Google Scholar 

  9. Sawin C.T., Geller A., Wolf P.A. et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N. Engl. J. Med. 1994, 331: 1249–1252.

    Article  PubMed  CAS  Google Scholar 

  10. Biondi B., Fazio S., Carella C. et al. Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine. J. Clin. Endocrinol. Metab. 1993, 77: 334–338.

    PubMed  CAS  Google Scholar 

  11. Erikson E.F., Mosekilde L., Melsen F. Trabecular bone remodeling and bone balance in hyperthyroidism. Bone 1985, 6: 421–428.

    Article  Google Scholar 

  12. Bartalena L., Pinchera A., Marcocci C. Management of Graves’ ophthalmopathy: reality and perspectives. Endocr. Rev. 2000, 21: 168–199.

    PubMed  CAS  Google Scholar 

  13. Marcocci C., Gianchecchi D., Masini I. et al. A reappraisa of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of Graves’ hyperthyroidism. J. Endocrinol. Invest. 1990, 13: 513–520.

    Article  PubMed  CAS  Google Scholar 

  14. Andrade V.A., Gross J.L., Maia A.L. The effect of methimazole pretreatment on the efficacy of radioactive iodine therapy in Graves’ hyperthyroidism: one-year follow-up of a prospective, randomized study. J. Clin. Endocrinol. Metab. 2001, 86: 3488–3493.

    PubMed  CAS  Google Scholar 

  15. Alexander E.K., Larsen P.R. High dose 131I therapy for the treatment of hyperthyroidism caused by Graves’ disease. J. Clin: Endocrinol. Metab. 2002, 87: 1073–1077.

    CAS  Google Scholar 

  16. Imseis R.E., Vanmiddlesworth L., Massie J.D., Bush A.J., Vanmiddlesworth N.R. Pretreatment with propylthiouracil, but not methimazole reduces the therapeutic efficacy of iodine-131 in hyperthyroidism. J. Clin. Endocrinol. Metab. 1998, 83: 685–687.

    Article  PubMed  CAS  Google Scholar 

  17. Sabri O., Zimny M., Schulz G. et al. Success rate of radioiodine therapy in Graves’ disease: the influence of thy-rostatic medication. J. Clin. Endocrinol. Metab. 1999, 84: 1229–1233.

    PubMed  CAS  Google Scholar 

  18. Kaplan M.M., Meier D.A., Dworkin H.J. Treatment of hyperthyroidism with radioactive iodine. Endocrinol. Metab. Clin. North Am. 1998, 27: 205–221.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luigi Bartalena.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bogazzi, F., Martino, E. & Bartalena, L. Antithyroid drug treatment prior to radioiodine therapy for Graves’ disease: Yes or no?. J Endocrinol Invest 26, 174–176 (2003). https://doi.org/10.1007/BF03345148

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03345148

Key words

Navigation