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The regioselective Synthesis of bromochlorins related to chlorophyll-a from methyl pheophorbide-a

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Abstract

An efficient methodology has been developed for the regioselective synthesis of brominated chlorins related to chlorophyll-a from methyl pheophorbide-a. Several regioselective bromination reactions were accomplished by some particular reaction conditions and a series of conversion of functional group from methyl pheophorbide-a to synthesize mono-, bis- and tri-brominated chlorines. The possible mechanisms for the debromination were tentatively proposed and the structures of all new chlorins were characterized by elemental analysis, IR, UV-Vis and 1H NMR spectra.

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Authors and Affiliations

  1. Science and Engineering College of Chemistry and Biology, Yantai University, Yantai, 264005, P. R. China

    J. J. Wang, J. Z. Li & F. G. Li

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  1. J. J. Wang
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  2. J. Z. Li
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  3. F. G. Li
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Correspondence to J. J. Wang.

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Wang, J.J., Li, J.Z. & Li, F.G. The regioselective Synthesis of bromochlorins related to chlorophyll-a from methyl pheophorbide-a . JICS 8, 1139–1145 (2011). https://doi.org/10.1007/BF03246572

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  • DOI: https://doi.org/10.1007/BF03246572

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