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NaI readily mediated oxidative aromatization of Hantzsch 1,4-dihydropyridines with hydrogen peroxide at room temperature: A green procedure

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Abstract

The oxidative conversion of 1,4-dihydropyridines to give the corresponding pyridine derivatives in excellent yields was easily effected using the catalytic amount of NaI in combination with H2O2 (30%) as a green external oxidant. The process is highly green wherein the solid products are easily filtered out after the addition of ice-water to the reaction mixture. This non-transition metal catalyst is cost-effective, affords simple work-up and easy separation of the product.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Yazd University, Yazd, 89195-741, Iran

    D. Shahabi, M. A. Amrollahi & A. A. Jafari

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  1. D. Shahabi
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  2. M. A. Amrollahi
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  3. A. A. Jafari
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Correspondence to M. A. Amrollahi.

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Shahabi, D., Amrollahi, M.A. & Jafari, A.A. NaI readily mediated oxidative aromatization of Hantzsch 1,4-dihydropyridines with hydrogen peroxide at room temperature: A green procedure. JICS 8, 1052–1057 (2011). https://doi.org/10.1007/BF03246562

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  • DOI: https://doi.org/10.1007/BF03246562

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