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One-Pot Synthesis of 1-Aminophosphinic acids using 50% Hypophosphorus Acid under microwave irradiation

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Abstract

A simple and efficient method has been developed for the synthesis of α-aminophosphinic acids from hypophosphorus acid under solvent-free conditions using microwave irradiation. α-Aminophosphinic acids were obtained in high yield under mild conditions by reaction of hypophosphorus acid with aldehydes in the presence of amines under microwave irradiation.

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Authors and Affiliations

  1. Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), Gava Zang, Zanjan, Iran

    B. Kaboudin & E. Jafari

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  1. B. Kaboudin
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  2. E. Jafari
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Correspondence to B. Kaboudin.

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Dedicated to Professor Habib Firouzabadi on the occasion of his 65 birthday and also his retirement

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Kaboudin, B., Jafari, E. One-Pot Synthesis of 1-Aminophosphinic acids using 50% Hypophosphorus Acid under microwave irradiation. JICS 5 (Suppl 1), S97–S102 (2008). https://doi.org/10.1007/BF03246496

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  • DOI: https://doi.org/10.1007/BF03246496

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