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Research progress of the endocrine disrupting activities of polychlorinated biphenyls

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Chinese Science Bulletin

Abstract

Polychlorinated biphenyls (PCBs) are global persistent organic pollutants. Almost all commercial PCBs mixtures, single PCB congener, and their metabolites possess endocrine disrupting activities. They can disrupt the estrogen/androgen system, thyroid hormone system and other endocrine systems by interfering with the synthesis, transport, storage, metabolism, and feedback regulation of hormones. The newest data related to the endocrine disrupting activities of PCBs and their mechanisms are reviewed and the research perspectives are also discussed.

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Authors and Affiliations

  1. Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 100085, Beijing, China

    Jingming Zhou, Zhanfen Qin, Cong Lin & Xiaobai Xu

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  1. Jingming Zhou
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  2. Zhanfen Qin
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  3. Cong Lin
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  4. Xiaobai Xu
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Correspondence to Xiaobai Xu.

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Zhou, J., Qin, Z., Lin, C. et al. Research progress of the endocrine disrupting activities of polychlorinated biphenyls. Chin.Sci.Bull. 49, 215–219 (2004). https://doi.org/10.1007/BF03182800

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  • DOI: https://doi.org/10.1007/BF03182800

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