Abstract
In-vivo dosimetry is an important technique to ensure accuracy of delivered dose during total body irradiation (TBI). We present an analysis of semiconductor diode dosimetry, constituting seven years of dosimetry data from eighty-six patients who underwent total body irradiation. For lateral field irradiation, the mean exit dose, averaged over five anatomical sites (head, sternal notch, chest, abdomen and pelvis) and as a percentage of the planned dose was 95.7 % (SD 7.8 %). For AP/PA irradiation, the mean exit dose averaged over five anatomical sites and as a percentage of the planned dose was 95.5 % (SD 9.8 %). We propose a number of possible reasons for these differences, including patient setup variations, movement of the patient and diodes during treatment, imprecise placement of planned bolus material, inaccurate inhomogeneity corrections and modelling by the treatment planning system.
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References
Metcalfe, P., Kron, T. and Hoban,P.,The Physics of Radiotherapy X-rays from Linear Accelerators. Medical Physics Publishing Corporation, 1997.
Planskoy, B., Tapper, P., Bedford, A. and Davis, F.,Physical aspects of total-body irradiation at the Middlesex Hospital (UCL group of hospitals), London 1988-1993: II. In vivo planning and dosimetry. Phys. Med. Biol. 41:2327–2343, 1996.
Mangili, P., Fiorino, C., Rosso, A., Cattaneo, G.M., Parisi, R., Villa, E. and Calandrino, R.,In vivo dosimetry by diode semiconductors in combination with portal films during TBI: reporting a 5-year clinical experience. Radiother. Oncol. 52:269–276, 1999.
Ribas, M., Jornet, N., Eudaldo, T., Carabante, D., Duch, M.A., Ginjaume, M., Gomez de Segura G. and Sanchez-Doblado, F.,Midplane dose determination during total body irradiation using in vivo dosimetry. Radiother. Oncol. 335:91–98, 1998.
Briot, E., Dutreix, A. and Bridier, A.,Dosimetry for total body irradiation. Radiother. Oncol. 18 Suppl. 1:16–29, 1990.
Hoogenhout, J., Brouwer, W.F., van Gasteren, J.J., Schattenberg, A., de Witte, T., van Daal, W.A. and Haanen, C.A.,Clinical and physical aspects of total body irradiation for bone marrow transplantation in Nijmegen. Radiother. Oncol. 18 Suppl. 1:118–120, 1990.
Vrtar, M. and Kovacevic, N.,A model of in vivo dosimetry and quality assurance analysis of total body irradiation in Zagreb. Acta Med Croatica. 52(1):15–26, 1998.
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Lancaster, C.M., Crosbie, J.C. & Davis, S.R. In-vivo dosimetry from total body irradiation patients (2000–2006): results and analysis. Australas. Phys. Eng. Sci. Med. 31, 191–195 (2008). https://doi.org/10.1007/BF03179343
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DOI: https://doi.org/10.1007/BF03179343