Skip to main content
Log in

Thallium and FDG uptake by atelectasis with bronchogenic carcinoma

  • Case Report
  • Published:
Annals of Nuclear Medicine Aims and scope Submit manuscript

Abstract

We report a case of bronchogenic carcinoma with atelectasis studied by Tl-SPECT and FDG-PET. In the carcinoma, abnormally high uptake of Tl and FDG were detected, but in the region of atelectasis, an abnormally high uptake of Tl with a relatively low uptake of FDG were observed. On quantitative analyses, the Tl retention indexes of the tumor and atelectasis were 29.7 and 42.0. The mean SUVs of FDG of the tumor and the atelectasis were 8.92 and 1.28. Tl-SPECT could not distinguish the atelectasis from the carcinoma. FDG-PET was superior to Tl-SPECT in this case in detecting malignancy and distinguishing it from atelectasis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Tonami N, Yokoyama K, Shuke J, Taki S, Kinuya S. Miyauchi T, et al. Evaluation of suspected malignant pulmonary lesions with201Tl single photon emission computed tomography.Nucl Med Commun 14: 602–610, 1993.

    Article  PubMed  CAS  Google Scholar 

  2. Suga K, Kume N, Orihashi N, Nishiguchi K, Uchisako H, Matsumoto T, et al. Difference in201T1 accumulation on single photon emission computed tomography in benign and malignant thoracic lesions.Nucl Med Commun 14: 1071–1078, 1993.

    Article  PubMed  CAS  Google Scholar 

  3. Takekawa H, Takaoka K, Tsukamoto E, Kanegae K, Miller F, Kawakami Y. Thallium-201 single photon emission computed tomography as an indicator of prognosis for patients with lung carcinoma.Cancer 80: 198–203, 1997.

    Article  PubMed  CAS  Google Scholar 

  4. Gupta NC, Frank AR, Dewan NA, Redepenning LS, Rothberg ML, Mailliard JA. et al. Solitary pulmonarynodules: detection of malignancy with PET with 2-[F-18]-fluoro-2-deoxy-D-glucose.Radiology 184: 441–444, 1992.

    PubMed  CAS  Google Scholar 

  5. Patz EF Jr, Lowe VJ, Hoffman JM, Paine SS, Harris LK, Goodman PC. Persistent or recurrent bronchogenic carcinoma: detection with PET and 2-[F-18]-2-deoxy-D-glucose.Radiology 191: 379–382, 1994.

    PubMed  Google Scholar 

  6. Bury T. Dowlati A, Paulus P, Hustinx R, Radermecker M, Rigo P. Staging of non-small-cell lung cancer by wholebody fluorine-18 deoxyglucose positron emission tomography.Eur J Nucl Med 23: 204–206, 1996.

    Article  PubMed  CAS  Google Scholar 

  7. Sasaki M, Ichiya Y, Kuwabara Y, Akashi Y, Yoshida T, Fukumura T, et al. The usefulness of FDG positron emission tomography for the detection of mediastinal lymph node metastasis in patients with non-small cell lung cancer: a comparative study with X-ray computed tomography.Eur J Nucl Med 23: 741–747, 1996.

    Article  PubMed  CAS  Google Scholar 

  8. Lee JD, Lee BH, Kim SK, Chung KY, Shin DH, Park CY. Increased thallium-201 uptake in collapsed lung: a pitfall in scintigraphic evaluation of central bronchogenic carcinoma.J Nucl Med 35: 1125–1128, 1994.

    PubMed  CAS  Google Scholar 

  9. Caluser C, Macapinlac H, Healey J, Ghavimi F, Meyers P, Wollner N, et al. The relationship between thallium uptake, blood flow, and blood pool activity in bone and soft tissue tumors.Clin Nucl Med 17: 565–572, 1992.

    Article  PubMed  CAS  Google Scholar 

  10. Sehweil AM, McKillop JH, Milroy R, Wilson R, Abdel Dayem HM, Omar YT. Mechanism of201Tl uptake in tumors.Eur J Nucl Med 15: 376–379, 1989.

    Article  PubMed  CAS  Google Scholar 

  11. Hanada T, Isobe H, Saito T, Ogura S, Takekawa H, Yamazaki K, et al. Intracellular accumulation of thallium as a marker of cisplatin cytotoxicity in non small cell lung carcinoma: an application of inductively coupled plasma mass spectrometry.Cancer 83: 930–935, 1998.

    Article  PubMed  CAS  Google Scholar 

  12. Brismar T, Collins VP, Kesselberg M. Thallium-201 uptake relates to membrane potential and potassium permeability in human glioma cells.Brain Res 500: 30–36, 1989.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Joji Kawabe.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kawabe, J., Okamura, T., Shakudo, M. et al. Thallium and FDG uptake by atelectasis with bronchogenic carcinoma. Ann Nucl Med 13, 273–276 (1999). https://doi.org/10.1007/BF03164905

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03164905

Key words

Navigation