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Comparison of Indium-111-labeled leukocyte scintigraphy and Technetium-99m joint scintigraphy in rheumatoid arthritis and osteoarthritis

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Abstract

This study was undertaken to evaluate the use of Indium-111-labeled leukocyte (111In-WBC) imaging compared with Technetium-99m pertechnetate (99mTcCV) imaging in 19 patients with rheumatoid arthritis (RA) and 8 with osteoarthritis. Knee and wrist joints were evaluated for both radionuclides. The results indicated a good correlation of the clinical assessment of pain and swelling with joint uptake ratio (JUR) between111In-WBC and99mTcO −4 in RA and osteoarthritis patients. We observed a discrepancy in both imagings in “burned out” cases. It was concluded that a JUR of111In-WBC could distinguish active RA from inactive RA or osteoarthritis at a value of 1.15 and that the use of111In-WBC was a more reliable procedure than99mTcO −4 .

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Authors and Affiliations

  1. Department of Radiology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, 260, Chiba, Japan

    Kimiichi Uno, Kenji Saegusa, Yoshimi Anzai, Takashi Terauchi & Noboru Arimizu

  2. Department of Orthopedics, Chiba University School of Medicine, Japan

    Toru Suguro & Hidetsugu Moriya

  3. Chiba Rehabilitation Center, Japan

    Kunichi Nohira

  4. Central Division of Radiology, Chiba University Hospital, Japan

    Kazuichi Sato & Sadao Uematsu

Authors
  1. Kimiichi Uno
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  2. Toru Suguro
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  3. Kunichi Nohira
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  4. Hidetsugu Moriya
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  5. Kenji Saegusa
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  6. Yoshimi Anzai
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  7. Takashi Terauchi
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  8. Kazuichi Sato
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  9. Sadao Uematsu
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  10. Noboru Arimizu
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Uno, K., Suguro, T., Nohira, K. et al. Comparison of Indium-111-labeled leukocyte scintigraphy and Technetium-99m joint scintigraphy in rheumatoid arthritis and osteoarthritis. Ann Nucl Med 6, 247–251 (1992). https://doi.org/10.1007/BF03164662

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  • DOI: https://doi.org/10.1007/BF03164662

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