Summary
We describe a neonate with a complicated enterovirusinfection, which made a full recovery after intensive care treatment, immunoglobulines and pleconaril, a new and on compassionate use available antiviral drug against picornaviruses. New developments on diagnostics and treatment are discussed and a critical view of the therapy used in this case is given.
Samenvatting
Een neonaat wordt beschreven met een ernstig verlopen enterovirusinfectie die restloos herstelde, aansluitend aan intensieve ondersteunende therapie, immunoglobulinen en pleconaril, een nog niet geregistreerd anti-picornavirusmiddel. De laatste ontwikkelingen met betrekking tot de diagnostiek en behandeling van enterovirusinfecties in het algemeen worden besproken en er wordt een kritische blik geworpen op het gevoerde beleid.
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M.W.M. Eling, agio kindergeneeskunde, mw.dr. A.H. Cromme-Dijkhuis, kindercardiologe, mw. C. Buysse, kinderarts-intensiviste, dr. N.G. Hartwig, kinderarts-infectioloog, afdeling Kindergeneeskunde, Erasmus mc-Sophia Kinderziekenhuis, Rotterdam. Mw.dr. A.C.T.M. Vossen, arts-microbioloog, afdeling Virologie, Erasmus mc, Rotterdam.
Correspondentieadres: M.W.M. Eling, afdeling Kindergeneeskunde, Erasmus mc-Sophia Kinderziekenhuis, Postbus 2060, 3000 CB Rotterdam,
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Eling, M.W.M., Cromme-Dijkhuis, A.H., Buysse, C.M.P. et al. Neonatale enterovirusinfecties, een case report en nieuwe mogelijkheden voor diagnostiek en behandeling. KIND 72, 128–133 (2004). https://doi.org/10.1007/BF03061499
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DOI: https://doi.org/10.1007/BF03061499