Summary
Methoxyflurane anaesthesia in dogs produced respiratory depression, a gradual moderate decline in blood pressure with minimal changes in heart rate, and no significant effect on blood glucose or plasria adrenaline and noradrenaline levels. Hypercarbia induced an immediate hypotensive response-and caused sigruficant increases in both catecholamines; haemorrhage was followed by significant increases in plasma adrenaline. Blood glucose increased as a result of hypercarbia and haemorrhage during methoxyfluran0e anaesthesia.
Résumé
L’anesthésie au méthoxyflurane, chez Ies chiens, s’accompagne d’une dépression respiratoire, d’une chute modérée graduielle de la tension artérielle avec des changements minimes du rythme cardiaque mais elle demeure sans effet important sur le taux de glucose sanguin, pas plus que sur le taux d’adrénaline et de nora-drenaline plasmatiques. L’hypercarbie a entraîné une hypotension immédiate et a produit une augmentation importante des catechoJamines; 1’hémorragie a entraîné une augmentation importante du taux d’adrénaline plasmatique. Au cours de léanesthésie au méthoxyflurane, à cause de léhypercarbie et de 1’hémorragie, le taux deglucose sanguin a augmenté.
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in receipt of a Sir Edward W. Beatty Memprial Scholarship.
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Millar, R.A., Morris, M.E. A study of methoxyflurane anaesthesia. Canad. Anaesth. Soc. J. 8, 210–215 (1961). https://doi.org/10.1007/BF03028110
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DOI: https://doi.org/10.1007/BF03028110