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Inhibition of gastric secretion in man with urogastrone

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The American Journal of Digestive Diseases

Summary

The subcutaneous administration of a potent preparation of urogastrone to nine human subjects significantly reduced the gastric secretory response to histamine with regard to the volume of gastric juice, its acidity, and the output of free acid. This inhibitory action was obtained with no other observed effects than a mild local erythema and tenderness at the site of injection.

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Authors
  1. John S. Gray
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  2. E. Wieczorowski
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  3. A. C. Ivy
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Additional information

Aided in part by a grant from the Committee on Endocrinology of the National Research Council.

Presented before the American Physiological Society, New Orleans, March 5, 1940.

From the Department of Physiology and Pharmacology, Northwestern University Medical School, Chicago, 111.

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Gray, J.S., Wieczorowski, E. & Ivy, A.C. Inhibition of gastric secretion in man with urogastrone. Jour. D. D. 7, 513–515 (1940). https://doi.org/10.1007/BF03014581

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  • DOI: https://doi.org/10.1007/BF03014581

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