Abstract
The incidence of nausea and vomiting after strabismus surgery was studied in 64 children aged one to six years. incidence was determined in the post-anaesthesia recovery room (PARR), in the same day surgery (SDS) unit, and at home on days one and two after the operation. After induction of anaesthesia, the children received an intravenous injection of droperidol (50 μg·kg-1) or saline in a double-blind randomized fashion, and an intravenous injection of glycopyrrolate (7.5 μg·kg-1) or atropine (10 μg·kg’-1) in an open randomized fashion. The incidence of emetic symptoms was highest in the SDS unit and at home on day one. Droperidol slightly but significantly delayed awakening and was not, at least in this particular age group, associated with any difference in postoperative sickness. Despite theoretical advantages, glycopyrrolate offered no significant benefit over atropine as far as postoperative emesis was concerned.
Résumé
Nous avons étudié la fréquence des nausées et vomissements après chirurgie du strabisme chez un groupe d’enfants âgés de un à six ans. L’incidence de cette complication a été relevée à la salle de réveil, à l’hospitalisation d’un jour, et à la maison pendant les deux premiers jours après l’6;opération. Après induction de l’anesthésie au masque, les enfants recevaient une injection intraveineuse de droperidol (50 μ g·kg-1) ou de salin, à double insu, selon une distribution aléatoire, et une injection intraveineuse de glycopyrrolate (7.5 μg·kg-1) ou d’atropine (10μg·kg-1) d’une façon randomisée, mais connue de l’investigateur. L’incidence des nausées et vomissements a été maximale à l’hospitalisa-tion d’un jour et à la maison pendant le premier jour post-opératoire. Le droperidol a retardé le réveil de façon modeste, mais statistiquement significative et n’a en rien modifié l’évolution des nausées et vomissements post-opératoires. De même, le glycopyrrolate, malgré certains avantages théoriques, n’a pas diminué l’incidence de cette complication post-opératoire, comparativement à l’atropine.
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Hardy, JF., Charest, J., Girouard, G. et al. Nausea and vomiting after strabismus surgery in preschool children. Can Anaesth Soc J 33, 57–62 (1986). https://doi.org/10.1007/BF03010909
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DOI: https://doi.org/10.1007/BF03010909