Skip to main content
SpringerLink
Log in

Higher folate intake is related to lower risk of Alzheimer’s disease in the elderly

  • Clinical Neurosciences
  • Brief Communications
  • Published:
The Journal of Nutrition, Health & Aging

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer’s disease. N Engl J Med 2002;346:476–483.

    Article  PubMed  CAS  Google Scholar 

  2. Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol 2007;64:86–92.

    Article  PubMed  Google Scholar 

  3. Morris MC, Evans DA, Bienias JL, et al. Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch Neurol 2005;62:641–645.

    Article  PubMed  Google Scholar 

  4. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr 2007;85:193–200.

    PubMed  CAS  Google Scholar 

  5. McMahon JA, Green TJ, Skeaff CM, Knight RG, Mann JI, Williams SM. A controlled trial of homocysteine lowering and cognitive performance. N Engl J Med 2006;354:2764–2772.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Taub Institute for Research of Alzheimer’s Disease and the Aging Brain, Columbia University, New York, NY

    J. A. Luchsinger MD, M. -X. Tang & R. Mayeux

  2. Division of General Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY

    J. A. Luchsinger MD

  3. Division of Biostatistics, Joseph P. Mailman School of Public Health, Columbia University, New York, NY

    M. -X. Tang

  4. Division of Epidemiology, Joseph P. Mailman School of Public Health, Columbia University, New York, NY

    R. Mayeux

  5. Department of Medical Pathology, School of Medicine, University of California, Davis, CA

    J. Miller & R. Green

  6. Gertrude H. Sergievsky Center, Columbia University, New York, NY

    R. Mayeux

  7. Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY

    R. Mayeux

  8. Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY

    R. Mayeux

Authors
  1. J. A. Luchsinger MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. -X. Tang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Miller
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Green
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. Mayeux
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J. A. Luchsinger MD.

Additional information

Support for this work was provided by grants from the National Institutes of Health 2P30AG15294-06, AG07232, AG07702, 1K08AG20856-01, RR00645 from the Charles S. Robertson Memorial Gift for research on Alzheimer’s disease, from the Blanchette Hooker Rockefeller Foundation, and from the New York City Council Speaker’s fund for Public Health Research.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Luchsinger, J.A., Tang, M.X., Miller, J. et al. Higher folate intake is related to lower risk of Alzheimer’s disease in the elderly. J Nutr Health Aging 12, 648–650 (2008). https://doi.org/10.1007/BF03008276

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03008276

Keywords

Search

Navigation