Summary
1. By use of the technique described, it was found that the normal volume of the colon of adult rats is from 3.0 c.c. to 4.5 c.c.
2. The volume of the colons of rats maintained on a diet deficient in vitamin B1 for two months increased strikingly in 70 per cent of the animals.
3. No such change occurred in a control group maintained on a complete synthetic diet.
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References
Hargreaves, Florence, Fletcher, A. A., and Dickson, W. H.: Influence of diet on motor and trophic functions of colon in rats.Tr. Roy. Soc. Canada, 25:197–198, May, 1931.
Harris, R. S., and Bunker, J. W. M.: Roentgenographic study of gastro-intestinal motility in rachitic rats.Am. J. Roentgenol., 33:25–30, January, 1935.
Chase, E. F., and Sherman, H. C.: A quantitative study of determination of antineuritic vitamin B.J. Am. Chem. soc., 53:3506–3510, 1931.
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Sparks, M.I., Collins, E.N. The role of vitamin B1 in tonus of the large intestine. American Journal of Digestive Diseases and Nutrition 2, 618–620 (1935). https://doi.org/10.1007/BF03000956
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DOI: https://doi.org/10.1007/BF03000956