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The autoregulation of the gastric secretion

  • Experimental Physiology
  • Published:
The American Journal of Digestive Diseases

Summary

Introduction into the duodenum of 0.25 per cent hydrochloric acid or of gastric juice, diluted two to four times, inhibits the gastric secretion stimulated(a) through the parasympathetic nervous system or(b) by the presence in the intestine of food substances or the products of their digestion. The same effect was produced by the gastric glands. The theory is advanced that the passage of the acid chyme from the stomach into the duodenum causes the gastric secretion to diminish, this being an important factor in regulating the activity of the gastric glands.

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References

  • Babkin, B. P.: Die äussere Sekretion der Verdauungsdrüsen. 2nd ed., Berlin, 1928, p. 274 ff., 424 ff.

  • Bolton, C., and G. W. Goodhart:Jour. Physiol., 73:115, 1931.

    CAS  Google Scholar 

  • Bolton, C., and G. W. Goodhart:Jour. Physiol., 77:287, 1933.

    CAS  Google Scholar 

  • Ivy, A. C.:Amer. Jour. Dig. Dis. and Nutr., 2:58, 1935.

    Google Scholar 

  • Kosaka, T.; R. K. S. Lim; S. M. Ling, and A. C. Liu:Chin. Jour. Physiol., 6:107, 1932.

    CAS  Google Scholar 

  • Lim, R. K. S.:Quart. Jour. Exp. Physiol., 23:264, 1933.

    Google Scholar 

  • Lim, R. K. S.; S. M. Ling, and A. C. Liu:Chin. Jour. Physiol., 8:219, 1934.

    CAS  Google Scholar 

  • MacLean, H., and W. J. Griffiths:Jour. Physiol., 65:63, 1928 (a).

    CAS  Google Scholar 

  • MacLean, H., and W. J. Griffiths:Jour. Physiol., 66:356, 1928 (b).

    CAS  Google Scholar 

  • MacLean, H.; W. J. Griffiths, and B. W. Williams:Jour. Physiol., 65:77, 1928.

    CAS  Google Scholar 

  • Quigley, J. P.; H. J. Zettelman, and A. C. Ivy:Am. Jour. Physiol., 108:643, 1934.

    CAS  Google Scholar 

  • Rosemann, R.:Pfluger’s Arch., 118–467, 1907.

  • Rosemann, R.:Virchow’s Arch., 229:67, 1920–21.

    Article  CAS  Google Scholar 

  • Scott, H. G., and A. C. Ivy:Annals Surg., June: 1197, 1931.

  • Shemiakin, A. I.: Thesis, St. Petersburg, 1901.

  • Sokolov, A.: Thesis, St. Petersburg, 1904.

  • Walawski, J.:Medyc. Doswiadcz. i spoleczna, 11:348, 1930. (Abstract in French.)

    CAS  Google Scholar 

  • Webster, D. R.:Amer. Jour. Physiol., 90:718, 1929.

    CAS  Google Scholar 

  • Webster, D. R., and J. C. Armour:Trans. Roy. Soc. Canada, 26, Section V: 109, 1932 (a).

    Google Scholar 

  • Webster, D. R., and J. C. Armour:Canad. Med. Assoc. Jour., 27:240, 1932 (b).

    CAS  Google Scholar 

  • Wilhelmj, C. M.; L. C. Heinrich, and F. C. Hill:Proc. Soc. Exp. Biol. and Med., 31:969, 1934.

    CAS  Google Scholar 

  • Wilhelmj, C. M.; I. Neigus, and F. C. Hill:Amer. Jour. Physiol., 106:381, 1933.

    CAS  Google Scholar 

  • Wilhelmj, C. M.; I. Neigus, and F. C. Hill:Amer. Jour. Physiol., 107:490, 1934 (a).

    CAS  Google Scholar 

  • Wilhelmj, C. M.; I. Neigus, and F. C. Hill:Amer. Jour. Physiol., 108:197, 1934 (b).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Montreal, Canada

    J. J. Day M.D. & D. R. Webster M.D., Ph.D.

Authors
  1. J. J. Day M.D.
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  2. D. R. Webster M.D., Ph.D.
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From the Department of Physiology, McGill University, Montreal.

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Day, J.J., Webster, D.R. The autoregulation of the gastric secretion. American Journal of Digestive Diseases and Nutrition 2, 527–531 (1935). https://doi.org/10.1007/BF03000921

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  • DOI: https://doi.org/10.1007/BF03000921

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