Skip to main content
SpringerLink
Log in

One hundred and sixty-nine studies in gastric secretion during the night

  • Clinical Medicine: Diseases Of Digestion
  • Published:
The American Journal of Digestive Diseases

Summary and conclusions

1. The curve of gastric secretion during the night has been studied in 169 patients.

2. Normals have little or no free hydrochloric acid during the night.

3. Patients with duodenal, gastric, and jejunal ulcer have a high nocturnal curve and a high titre of free acid.

4. Gastric neuroses have a low nocturnal curve of secretion.

5. In gastric carcinoma, the gastric contents during the night resemble those found in the usual day test meal, i. e., a low acidity with increased mucus and blood.

6. The nocturnal hypersecretion and hyperchlorhydria in peptic ulcer cannot be controlled by alkalies, olive oil, atropine and aspiration.

7. In our opinion the best medical method of controlling the gastric secretion during the night is the milk drip. Surgically, partial gastrectomy frequently accomplishes the same result.

8. The significance of these findings particularly in the problem of peptic ulcer is discussed. Finally, the injurious effect on the gastric mucosa of an increased fastingor interdigestive secretion is emphasized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Bibliography

  1. Rehfuss, M. E., and Hawk, P. B.:J. A. M. A., 76:564; 1921.

    CAS  Google Scholar 

  2. Babkin, B. P.: Libman Anniversary Volumes, Vol. 1:113; 1932.

    Google Scholar 

  3. Enderlen and Redwitz, V.:Munchn. Med. Wachenschr., 49:1683; 1922.

    Google Scholar 

  4. Silbermann, I. S.:Zbl. Chir., 38:2385; 1927.

    Google Scholar 

  5. Moszowicz, L.:Arch. f. Klin. Chir., 122:444; 1922.

    Google Scholar 

  6. Chalfen, S. S.:Arch. f. Verdauungskr., 44:25; 1928.

    Google Scholar 

  7. Winkelstein, A.:Amer. J. Med. Sc., 5:185–695; 1933.

    Google Scholar 

  8. Winkelstein, A.: Annual Transactions Am. G. E. Assn., 36; 1933.

  9. Buchner, F.; Siebert, P., and Molloy, P. J.:Zeigler Beitr. Zur. Path. Anat., 81:391; 1928.

    Google Scholar 

  10. Puhl:Arch. Klin. Chir., 169:597; 1932.

    Google Scholar 

  11. Puhl and Brodersen:Arch. Klin. Chir., 168:30; 1932.

    Google Scholar 

  12. Palmer, W. L., and Heinz, T. E.:Arch. of Int. Med., 2:269; 1934.

    Google Scholar 

  13. Henning, N., and Norpoth, L.:Deutsch. Arch. f. Klin. Med., 172; Nos. 5, 6; 1932.

  14. Henning, N., and Norpoth, L.:Arch. f. Verdauungskr., 53:63; 1933.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. New York City, New York

    Asher Winkelstein

Authors
  1. Asher Winkelstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

From the Wimpheimer Wards for the Surgical Treatment of Gastrointestinal Diseases and the Medical Department of Mount Sinai Hospital.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Winkelstein, A. One hundred and sixty-nine studies in gastric secretion during the night. American Journal of Digestive Diseases and Nutrition 1, 778–782 (1934). https://doi.org/10.1007/BF02999604

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02999604

Keywords

Search

Navigation