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Does histamine stimulate the secretory activity of the peptic cells in man?

  • Experimental Physiology
  • Published:
The American Journal of Digestive Diseases

Conclusion

In the light of the data at our disposal, it seems reasonable to conclude that histamine does not augment the output of pepsin, and that “histamine” gastric secretion reflects the state of activity of the peptic cells before the injection of this substance. There seems to be no need therefore to suggest a new theory to explain the action of histamine on the human gastric glands. The conception formulated by previous investigators with respect to the gastric glands of carnivorous animals, namely, that histamine stimulates the parietal cells exclusively, may be safely applied to human gastric glands as well.

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Authors and Affiliations

  1. Montreal, Canada

    C. Gwendoline Toby B.A.

Authors
  1. C. Gwendoline Toby B.A.
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From the Department of Physiology, McGill University.

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Toby, C.G. Does histamine stimulate the secretory activity of the peptic cells in man?. American Journal of Digestive Diseases and Nutrition 3, 902–903 (1936). https://doi.org/10.1007/BF02999291

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  • DOI: https://doi.org/10.1007/BF02999291

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