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The secretion of chlorine ions in achlorhydric gastric juice

Observations by means of radioactive chlorine

  • Published:
The American Journal of Digestive Diseases

Summary

Chlorine ions, tagged by rendering them radioactive, were observed to pass readily from the blood stream into achlorhydric gastric juice. The relatively slower appearance of such ions in the achlorhydric juice as compared with the speed of passage previously observed when free acid was secreted by the gastric mucosa, would appear to be due to the relatively smaller volume of gastric secretion obtained from a mucosa not capable of secreting free acid.

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References

  1. Brunschwig, A., Clarke, T. H., Van Prohaska, J. and Kandel, E.: A Secretory Depressant in the Gastric Juice of Patients with Pernicious Anemia.J. Clin. Invest., 17:41B, 1939.

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  2. Brunschwig, A., Clarke, T. H., Van Prohaska, J. and Schmitz, E. L.: A Secretory Depressant in the Achlorhydric Gastric Juice of Patients with Carcinoma of the Stomach.S. G. O., 70:25, 1940.

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  5. Brunschwig, A. and Schmitz, R. L.: Rapidity of Passage of Chlorine Ion from Blood Into Gastric Juice of Stimulated Stomach.Proc. Soc. Exp. Biol. and Med., 43:438, 1940.

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Authors and Affiliations

  1. Departments of Surgery, Medicine and Physics, The University of Chicago, Chicago, Illinois

    Alexander Brunschwig, Robert L. Schmitz & Louis Slottin

Authors
  1. Alexander Brunschwig
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  2. Robert L. Schmitz
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  3. Louis Slottin
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Additional information

The observations reported in this paper are incidental to a study of achlorhydria in gastric cancer that is being conducted under grants from the International Cancer Research Foundation, Philadelphia, Pa. and the National Advisory Cancer Council of the U. S. Public Health Service, Washington, D. C.

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Brunschwig, A., Schmitz, R.L. & Slottin, L. The secretion of chlorine ions in achlorhydric gastric juice. Jour. D. D. 8, 171–173 (1941). https://doi.org/10.1007/BF02998284

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  • DOI: https://doi.org/10.1007/BF02998284

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