Medical Oncology

, Volume 13, Issue 3, pp 177–184 | Cite as

Clinical role of GM-CSF in neutrophil recovery in relation to health care parameters

  • L. S. Hofstra
  • E. G. E. De Vries
  • C. A. Uyl-De Groot
  • E. Vellenga


Recombinant human growth factors, particularly granulocyte-macrophage colony-stimulating factor (GM-CSF), have been only available for a few years. Since their introduction they have affected the management of drug-induced neutropenia, the use of dose intensive chemotherapy regimens and in the setting of autologous stem cell transplantation. This review addresses the clinical role of GM-CSF, using the data available, in neutrophil recovery in relation to various health care parameters.


GM-CSF neutrophil recovery health care 


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Copyright information

© Humana Press Inc. 1996

Authors and Affiliations

  • L. S. Hofstra
    • 1
  • E. G. E. De Vries
    • 1
  • C. A. Uyl-De Groot
    • 3
  • E. Vellenga
    • 2
  1. 1.Departments of OncologyThe Netherlands
  2. 2.Department of HematologyUniversity Hospital GroningenGroningenThe Netherlands
  3. 3.Institute for Medical Technology AssessmentErasmus UniversityRotterdamThe Netherlands

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