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Clinical role of GM-CSF in neutrophil recovery in relation to health care parameters

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Abstract

Recombinant human growth factors, particularly granulocyte-macrophage colony-stimulating factor (GM-CSF), have been only available for a few years. Since their introduction they have affected the management of drug-induced neutropenia, the use of dose intensive chemotherapy regimens and in the setting of autologous stem cell transplantation. This review addresses the clinical role of GM-CSF, using the data available, in neutrophil recovery in relation to various health care parameters.

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Authors and Affiliations

  1. Departments of Oncology, The Netherlands

    L. S. Hofstra & E. G. E. De Vries

  2. Department of Hematology, University Hospital Groningen, PO Box 30.001, 9700, Groningen, RB, The Netherlands

    E. Vellenga

  3. Institute for Medical Technology Assessment, Erasmus University, Rotterdam, The Netherlands

    C. A. Uyl-De Groot

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  1. L. S. Hofstra
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  2. E. G. E. De Vries
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  3. C. A. Uyl-De Groot
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  4. E. Vellenga
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Hofstra, L.S., Vries, E.G.E.D., Groot, C.A.UD. et al. Clinical role of GM-CSF in neutrophil recovery in relation to health care parameters. Med Oncol 13, 177–184 (1996). https://doi.org/10.1007/BF02990845

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