Abstract
The nasal passages form one of the chief sources of contact of man with his environment. Hence, it is natural that the mucosa of the area should be the victim of assault with multitudes of potential allergens in Man’s environment, and as a result allergic reactions ensue. The immunological concept cannot easily account for some of the significant facts surrounding this disease. Based on model experiments and other considerations, an alternative theory has been postulated for atopic allergy by Szentivanyi (1968) and co-workers. According to this view, the fundamental abnormality in such cases is a selective beta-adrenergic blockade.
The present study was undertaken to investigate whether the blockade of beta-adrenergic functions demonstrated in bronchial asthma (Cookson and Reed, 1963; Maselli et al., 1970; Fireman et al., 1970) holds true in other allergic conditions like nasal allergy and vasomotor rhinitis which has a striking clinical similarity to the former.
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Kakar, P.K., Arora, S., Lahiri, A.K. et al. Adrenergic functions in nasal allergy. Indian J Otolaryngol 28, 81–83 (1976). https://doi.org/10.1007/BF02990585
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DOI: https://doi.org/10.1007/BF02990585