Conclusions
Long-term monitoring of blood glucose in diabetic patients is a powerful tool in the clinical practice, and HbA1a-c assay is probably suitable for this purpose. The importance of this parameter requires a high degree of affidability together with routine feasibility. In this work we showed that a number of factors can interfere with the precision and accuracy of glycosylated hemoglobin detection by the presently investigated method. However, care in the storage of samples and in the control of the operating temperature may be easily obtained and lead to satisfactory results.
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References
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Trivelli L. A., Ranney H. M., Lai N. T.: Hemoglobin components in patients with diabetes mellitus - New Engl. J. Med.284, 353, 1971.
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This work was supported by a grant from theConsiglio Nationale delle Ricerche (CNR), Roma, Italy.
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Mosca, A., Carenini, A., Samaja, M. et al. Improvement of glycosylated hemoglobin measurement by disposable ion-exchange columns. La Ricerca Clin. Lab. 10, 251–253 (1980). https://doi.org/10.1007/BF02984935
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DOI: https://doi.org/10.1007/BF02984935