Abstract
The butanol extract ofPaulownia tomentosa stem showed antibacterial activity againstStaphylococcus aureus (SG511, 285 and 503),Streptococcus pyogenes (A308 and A77) andStreptococcus faecium MD8b etc. The most active compound of the extract was identified to be campneoside I, which had a minimal inhibitory concentration(MIC) of 150 μg/ml againstStreptococcus andStaphylococcus species. From such antibacterial activity, the methoxy group of campneoside I was postulated to be the essential element for the antibacterial activity.
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Adriani, C., Bonini, C., Iavarone, C. and Trogolo, C., Isolation and characterization paulownioside, a new highly oxygenated iridoid glucoside fromPaulownia tomentosa.J. Nat. Prod., 44, 739–744 (1981).
Andary, C., Wylde, R., Laffite, C., Privat, G. and Winrernitz, F., Structures of Verbascoside and Orobanchoside, Caffeic acid sugar esters fromOrobanche rapum-genistae.Phytochemistry, 21(5), 1123–1127 (1982).
Bae, K., Kim, B., Myung, P., Chung, K. and Baek, J., The isolation and evaluation of bioactive components from crude drugs against a cariogenic bacterium,Streptococcus mutans OMZ 176; an antibacterial component of Polyogoni Radix and its safety.Yakhak Hoeji, 34, 277–281 (1990).
Chinese Drugs Encyclopedia Vol. III. Sanghai Sci. Tech. Press. p. 1925 (1985).
Gering, B. and Wichtl, M., Phytochemical investigations on Penstemon hirsutus.J. Nat. Prod., 50(6), 1048–1051 (1987).
Hegnauer, R. and Kooiman, P.,Planta Med., 33, 1–5 (1978).
Imakura, Y., Kobayashi, S. and Mima, A., Bitter phenylpropanoid glycosides fromCampsis chinensis.Phytochemistry, 24(1), 139–146 (1985).
Ina, H., Ono, M., Sashida, Y. and Iida, H., (+)-piperitol fromPaulownia tomentosa.Planta Med., 53, 504 (1987).
James, C., William, G. D., Adi, F. G., John, D. M. and James, B. M., Evaluation of a tetrazolium-based semiautomated colorimetric assay; Assessment of Chemosensitivity Testing.Cancer Research, 47, 936–939 (1987).
Jang, S. K., Park, Y. M., Kim, Y. S., Kang, K. H., Kim, Y. S. and Kim, B.-K., Study on constituents ofPaulownia tomentosa Stem (II).Yakhak Hoeji, 35(6), 483 (1991).
Kitagawa, S., Tsukamoto, H., Hisada, S. and Nishibe, S., Studies on the Chinese Crude Drug “Forsythiae Fructus”. VII. A new caffeoyl glycoside fromForsythia viridissima.Chem. Pharm. Bull., 32(3), 1209–1213 (1984).
Kitagawa, S., Nishibe, S. and Baba, H., Studies on the Chinese Crude Drug “Forsythiae Fructus”. VIII.Yakugaku Zasshi, 107, 274 (1987).
Kobayashi, H., Oguchi, H., Takizawa, N., Miyase, T., Ueno, A., Usmanghani, K. and Ahmad, M., New Phenylethanoid glycosides fromCistanche tubulosa (Schrenk) Hook. f.l..Chem. Pharm. Bull., 35(8), 3309–3311 (1987).
Miyase, T., Koizumi, A., Ueno, A., Noro, T., Kuroyanagi, M., Fukushima, S., Akiyama, Y. and Takemoto, T., Studies on the Acyl Glycosides fromLeucoseptrum japonicum (miq) Kitamura et Murata.Chem. Pharm. Bull., 30(8), 2732–2734 (1982).
Namba, T., Tsunezuka, M., Bae, K. and Hattori, M., Studies on dental caries prevention by traditional Chinese medicines (part I); Screening of crude drugs for antibacterial action againstStreptococcus mutans.Shoyakugaku Zasshi, 35, 295–301 (1981).
Park, I. Y., Kim, B.-K. and Kim, Y. B., Constituents ofPaulownia tomentosa Stem (III).Arch. Pharm. Res., 15(1), 52–57 (1992).
Park, Y. M., Jang, S. K., Kim, Y. S. and Kim, B.-K., The constituents ofPaulownia tomentosa Stem.Yakhak Hoeji 35, 301–307 (1991).
Sasaki, H., Nishimura, H., Chin, M. and Mitsuhashi, H., Hydroxycinnamic acid esters of phenethylalcohol glycosides fromRehmannia glutinosa var.purpurea.Phytochemistry, 28(3), 875–879 (1989).
Sasaki, H., Taguchi, H., Endo, T., Yosioka, I., Higashiyama, K., and Otomas, H., The glycosides ofMartynia louisiana Mill. A new phenylpropanoid glycoside, martynoside.Chem. Pharm. Bull., 26(7), 2111–2113 (1978).
Seo, W., Koo, S. and Bae, K., Antimicrobial activities of hydroxybiphenyl derivatives.Arch. Pharm. Res., 9, 127–130 (1986).
Shoyama, Y., Matsumoto, M. and Nishioka, I., Phenolic Glycosides from diseased roots ofRehmannia glutinosa var.purpurea.Phytochemistry, 26(4), 983–986 (1987).
Sticher, O. and Lahloub, M. F.,Planta Med., 46, 145 (1982).
Takahashi, K., Tanabe, Y., Xobayashi, K. and Nakagawa, N., Studies on constituents of medical plant(4), chemical structure of paulownin, a component of wood ofPaulownia tomentosa Steud.Yakugaku Zasshi, 83, 1101–1105 (1963).
Yamauchi, T., Date, H., Saihara, Y. and Osaka, K., Deodorants containing hydrogen peroxide and plant extracts.Japan Kokai Tokkyo Koho JP 62, 87, 357–362 (1987).
Yoneiti, K. and Sawada, H., Constituents of the bark ofPaulownia tomentosa Steud.Yakugaku Zasshi, 79, 1226–1229 (1959).
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Kang, K.H., Jang, S.K., Kim, BK. et al. Antibacterial phenylpropanoid glycosides fromPaulownia tomentosa Steud. Arch. Pharm. Res. 17, 470–475 (1994). https://doi.org/10.1007/BF02979128
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DOI: https://doi.org/10.1007/BF02979128