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In Vitro Anti-Helicobacterpylori activity of Panaxytriol isolated from Ginseng

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  • Medicinal Chemistry & Natural Products
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Abstract

This study investigated the effect that some polyacetylenes and protopanaxatriol, which were isolated from heated ginseng (family Araliaceae), have on inhibitingHelicobacter pylori (HP) growth. Among the compounds tested, panaxytriol was quite effective in inhibiting HP growth with an MIC of 50 μg/ml. Ginsenoside Rh1 and protopanaxatriol weakly inhibited H+/K+-ATPase from a rat stomach.

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Correspondence to Dong-Hyun Kim.

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Bae, EA., Han, M.J., Baek, NI. et al. In Vitro Anti-Helicobacterpylori activity of Panaxytriol isolated from Ginseng. Arch Pharm Res 24, 297–299 (2001). https://doi.org/10.1007/BF02975095

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  • DOI: https://doi.org/10.1007/BF02975095

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