Abstract
Several new coumarinoyl pyrazole and coumarionyl-1,2,4-triazole derivatives were synthesised via dipolar cycloaddition reactions with 3-coumarinohydraziodoyl halide. Structure were based on elemental analysis and spectral data.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References Cited
Cingolani, G. M., Gualtieri, F. and Pigini, M., Research in the field antiviral compounds Mannich bases of 3-hydroxy coumarin.J. Med. Chem., 12, 531–532 (1969).
Essawy, A. I., Elkady, M. and Mohamed, A. Y., Some reactions of 3-cinnamoylcoumarins.Indian J. Chem., 19B, 567–570 (1980).
Ezmirly, S. T. and Shawali, A. S., The regioselectivity in the reactions of N-aryl-C-ethoxy carbonyl nitrilimines with acrylic acid derivatives.J. Heteroclic Chem., 25, 257–263 (1988).
Fliege, W., Grashy, R. and Huisgen, R., 1,3-Dipolare cycloaddition. Die Chemie des N-Methyl-C-Phenyl nitrilimines.Chem. Ber., 117, 1194–1214 (1984).
Ismail, N. A., Reactions with coumarinohydrazidoyl halides: Synthesis of several new coumarin, 1,3,4-thiazole, Benzo-1,4-oxazine and benzo-1,4-thiazine derivatives.Egypt J. Pharm. Sci., 32, 961–970 (1991).
Ismail, N. A., Reactions with coumarin derivatives: Synthesis of several new coumarinopyrazoles, coumarinopyridines and coumarinyl azoles.Egypt J. Pharm. Sci., 32, 685–693 (1991).
Ismail, N. A., Khalifa, F. A. and Magd El-Din, A. A., Reactions with coumarins: Synthesis of several new annelated pyridine and pyrrolylocumarin derivatives.Heterocycles, 32(6), 1101–1107 (1991).
Koelsch, C. F., Bromination of 3-acetocumarine.J. Am. Chem. Soc., 72, 2993–2995 (1950).
Mathur, C. N., Mitra, C. R., Krishnaswamy, N. R., Kulshreshtha, R. K. and arora, R. B., Effect of some coumarin derivatives on the coronary flow and their structure-activity relation.Arch. Intern. Pharm., 153(1), 218–225 (1965).
Shawali, A. S., Hassaneen, H. M., Ibrahim, H. A., Mekki, S. T. and Fahmi, A. A., Synthesis and cycloaddition reactions of N-aryl-2-furohydrazonyl chlorides.Arch. Pharm. Res., 13(2), 126–131 (1990).
Tewari, R. S. and Parihar, P., 1,3-Dipolar cycloaddition and nucleophilic substitution reaction of C-acetyl and C-ethoxy. Caronyl derivative of hydrazidoyl bromides.Tetrahedron, 39(1), 129–136 (1983).
Tewari, R. S., Dixit, P., Dubey, D. and Ajoy, K., Studies on 1,3-dipolar cycloaddition reactions of some cycloimmonium ylides.J. Chem. Eng., Data, 28, 283–285 (1983).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ismail, N.A., Eldin, S.M. & Fikry, R.M. Reactions with coumarinohydrazidoyl halides: Synthesis of some new coumarinoyl pyrazole and 1,2,4-traizole derivativies via dipolar cycloaddition reactions. Arch. Pharm. Res. 16, 251–253 (1993). https://doi.org/10.1007/BF02974491
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02974491