Skip to main content
SpringerLink
Log in

Synthesis and pharmacological activity of 3-[(p-acetamidoalkyl) benzenesulfonyl]-thiazolidin-4-ones and thiazolines

  • Research Articles
  • Published:
Archives of Pharmacal Research Aims and scope Submit manuscript

Abstract

Two series of substituted sulfonylthiazolidin-4-ones and sulfonylthiazolines have been synthesized and examined for their antidiabetic and biological aticity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References Cited

  • Bott-Handford, R. and Heath, H., The effect of aldose reductase inhibitors on thee metabolism of cultured monkey kidney epithelial cells.Biochem. Pharmacol. 30, 3065 (1981).

    Article  Google Scholar 

  • Bott-Handford, R. and Heath, H., Identification of fractose as the retinopathic agent associated with the ingestion of sucrose-rich diets in the rate.Metabolism, 29, 1247 (1980).

    Article  Google Scholar 

  • Boutwell, J. H. Jr.,Clin. Chem. Lab. Manual and Method, Philadelphia Lea & Febriger, 1961, pp. 283.

    Google Scholar 

  • El-Kerdawy, M. M. and El-Kousy, S., Preparation of certain 1[4-(acetamidomethyl) bmrenesulfonyl urea] and thiourea derivatives.Bull. Fac. Pharm. Cairo Univ. 12, 248 (1975).

    Google Scholar 

  • Eltahir, K. E. H., Al-Obeid, H. A., Al-Rashood, K. A., Madani, A. E. and Ageel, A. M., The antiarrhythmic activity of N-alkyl-1,2-dipheenylethanolamines.Pharmac. Res. 6, 252 (1989).

    Article  CAS  Google Scholar 

  • Hoechst, F., Preparation of sulfonylureas.Chem. Abstr. 62, 6131h (1965).

    Google Scholar 

  • Peterson, U. J., Sarges, R., Aldinger, C. E. and MacDonald, D. P., A novel aldose reductase inhibitors that inhibits polyol pathway activity in diabetic and galactosenic rates.Metabolism, 28, 456 (1979).

    Article  PubMed  CAS  Google Scholar 

  • Sohda, T., Mizuno, K., Imamiya, E., Sugiyama, Y., Fujita, T. and Kawamatsu, Y., Studies on antidiabetic agents 11. Synthesis of 5-[4-(1-methyl cyclohexylmethoxy)-benzyl]thiazolidine-2,4-dione and its derivatives.Chem. Pharm. Bull. 30, 3580 (1982).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyaddh, Saudi Arabia

    Hamad A. Al-Khamees, Hesham A. Kandil & Said M. Bayomi

  2. Department of Pharmacology, College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyaddh, Saudi Arabia

    Kamal E. H. El-Tahir

Authors
  1. Hamad A. Al-Khamees
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hesham A. Kandil
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kamal E. H. El-Tahir
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Said M. Bayomi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Al-Khamees, H.A., Kandil, H.A., El-Tahir, K.E.H. et al. Synthesis and pharmacological activity of 3-[(p-acetamidoalkyl) benzenesulfonyl]-thiazolidin-4-ones and thiazolines. Arch. Pharm. Res. 16, 186–190 (1993). https://doi.org/10.1007/BF02974480

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02974480

Key words

Search

Navigation