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Effects of squalene on the immune responses in mice(II): Cellular and non-specific immune response and antitumor activity of squalene

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Abstract

Effects of squalene on cellular and non-specific immune responses and antitumor activity in mice were investigated. Cellular and non-specific immunological assay parameters adopted in the present study were delayed-type hypersensitivity reaction and rosette forming cells (RFC) for cellular immunity, activities of natural killer (NK) cells and phagocyte for non-specific immunity. Squalene resulted in marked increases of cellular and non-specific immune functions and enhancement of host resistance to tumor challenge in dose-dependent manner.

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  1. College of Pharmacy, Won Kwang University, 570-749, Iri, Korea

    Young Keun Ahn & Joung Hoon Kim

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  1. Young Keun Ahn
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Ahn, Y.K., Kim, J.H. Effects of squalene on the immune responses in mice(II): Cellular and non-specific immune response and antitumor activity of squalene. Arch. Pharm. Res. 15, 20–29 (1992). https://doi.org/10.1007/BF02973979

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