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Reactions with hydrazidoyl halides VIII: Synthesis of thiazolo [3,2-a] benzimidazoles, imidazo[2,1-b] thiazoles and imidazo[2,1-b] benzthiazoles

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Abstract

Hydrazidoyl halides were condensed with 2-mercaptobenzimidazole2 yielding4a-c which were cyclized to the corresponding 3-substituted 2-arylazothiazolo-[3,2-a] benzimidazole6a-c, respectively. Imidazo-[2,1-b] thiazoles9, 12, 15, and16 were obtained by the reaction of hydrazidoyl halides1 with 2-mercapto 4,5-dihydroimidazole3 and 2-aminothiazoles10. The structures of the products were established on the basis of their elemental analysis and spectral data studies.

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Author notes

  1. Abdou O. Abdelhamid

    Present address: Department of Chemistry, Faculty of Science, University of Cairo, Cairo, Egypt

Authors and Affiliations

  1. Department of Scienc, King Khalid Military Academy, P. O. Box 2214o, 11495, Riyadh, Saudi Arabia

    Fikry A. Abdel-Mohdy & Abdou O. Abdelhamid

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  1. Fikry A. Abdel-Mohdy
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  2. Abdou O. Abdelhamid
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Abdel-Mohdy, F.A., Abdelhamid, A.O. Reactions with hydrazidoyl halides VIII: Synthesis of thiazolo [3,2-a] benzimidazoles, imidazo[2,1-b] thiazoles and imidazo[2,1-b] benzthiazoles. Arch. Pharm. Res. 15, 9–13 (1992). https://doi.org/10.1007/BF02973977

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  • DOI: https://doi.org/10.1007/BF02973977

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