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Meiotic recombination in filamentous fungi

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Abstract

The exchange of genes by crossing over and by gene conversion is a basic process in eukaryotes. Fungi have played a special role in the study of this process because they permit tetrad analysis, which provides complete information on the distribution of genes and chromosomes in meiosis. Recombination is detected by new combinations of genetic markers. The first observation gave only the simple picture of a crossover provided by two segregating loci far apart on the chromosome. Later the discovery of recombination between sites within a gene led to a revolution in our knowledge of this process. Today we carry the resolution a step further with RFLP markers, which can detect the details of recombination down to nucleotide distances. I review here observations on filamentous fungi, which have contributed to this pursuit at each stage of the emerging synthesis.

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  1. Department of Genetics, University of Washington, 98195-7360, WA, Seattle, USA

    David R. Stadler

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Stadler, D.R. Meiotic recombination in filamentous fungi. J. Genet. 75, 265–280 (1996). https://doi.org/10.1007/BF02966307

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