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Studies on the constituents of higher fungi of Korea(XXIII)

Antineoplastic activities ofCoriolus versicolor (L. ex Fr.) Quél.,Pleurotus ostreatus (Fr.) Kummer andLentinus edodes (Berk.) Sing.

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Abstract

The carpophores of three Korean mushrooms,Coriolus versicolor, Pleurotus ostreatus andLentinus edodes were respectively extracted with hot water and the extracts were dialyzed through Visking tube. They were found to exert an antitumor activity against sarcoma-180 implanted in mice. Especially, the inhibition ratio of the extract ofCoriolus versicolor (100 mg/Kg, i.p.) was almost 100%. But all the extracts did not affect the growth of leukemia L5187Y cellsin vitro. Therefore these facts indicate that the extracts appear to stimulate cell-mediated immunity.

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  1. Department of Microbial Chemistry, College of Pharmacy, Seoul National University, 151, Seoul, Korea

    Byong Kak Kim, Eun Kyue Park & Mi Ja Shim

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  1. Byong Kak Kim
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  2. Eun Kyue Park
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Kim, B.K., Park, E.K. & Shim, M.J. Studies on the constituents of higher fungi of Korea(XXIII). Arch. Pharm. Res. 2, 145–151 (1979). https://doi.org/10.1007/BF02959042

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